[HTML][HTML] Nanotechnology based drug delivery systems for the treatment of anterior segment eye diseases

AL Onugwu, CS Nwagwu, OS Onugwu… - Journal of Controlled …, 2023 - Elsevier
Diseases affecting the anterior segment of the eye are the primary causes of vision
impairment and blindness globally. Drug administration through the topical ocular route is …

Dendrimer-based drug delivery systems: History, challenges, and latest developments

J Wang, B Li, L Qiu, X Qiao, H Yang - Journal of Biological Engineering, 2022 - Springer
Since the first dendrimer was reported in 1978 by Fritz Vögtle, dendrimer research has
grown exponentially, from synthesis to application in the past four decades. The distinct …

Nanogels: Synthesis, properties, and recent biomedical applications

QY Duan, YX Zhu, HR Jia, SH Wang, FG Wu - Progress in Materials …, 2023 - Elsevier
Nanogels, also termed hydrogel nanoparticles, have the properties and functions of both
nanomaterials and hydrogels. Till date, a considerable number of nanogels have been …

Nanotechnology-based ocular drug delivery systems: recent advances and future prospects

S Li, L Chen, Y Fu - Journal of Nanobiotechnology, 2023 - Springer
Ocular drug delivery has constantly challenged ophthalmologists and drug delivery
scientists due to various anatomical and physiological barriers. Static and dynamic ocular …

Screening of carbonic anhydrase, acetylcholinesterase, butyrylcholinesterase, and α-glycosidase enzyme inhibition effects and antioxidant activity of coumestrol

L Durmaz, A Erturk, M Akyüz, L Polat Kose, EM Uc… - Molecules, 2022 - mdpi.com
Coumestrol (3, 9-dihydroxy-6-benzofuran [3, 2-c] chromenone) as a phytoestrogen and
polyphenolic compound is a member of the Coumestans family and is quite common in …

Application of dendrimers in anticancer diagnostics and therapy

Z Bober, D Bartusik-Aebisher, D Aebisher - Molecules, 2022 - mdpi.com
The application of dendrimeric constructs in medical diagnostics and therapeutics is
increasing. Dendrimers have attracted attention due to their compact, spherical three …

Multifunctional stimuli-responsive niosomal nanoparticles for co-delivery and co-administration of gene and bioactive compound: In vitro and in vivo studies

NA Abtahi, SM Naghib, SJ Ghalekohneh… - Chemical Engineering …, 2022 - Elsevier
This study aims to optimize niosomes for carrying and delivering the anticancer agents and
genes, simultaneously. We synthesized new cationic niosomal formulations containing …

Zwitterionic targeting doxorubicin-loaded micelles assembled by amphiphilic dendrimers with enhanced antitumor performance

L Zhang, Q Guo, R Zheng, Q Yu, Y Liang, G Ma, Q Li… - Langmuir, 2023 - ACS Publications
Chemotherapy is the main method of treating malignant tumors in clinical treatment.
However, the commonly used chemotherapeutic drugs have the disadvantages of high …

Solubilization of chitosan in biologically relevant solvents by a low-temperature solvent-exchange method for developing biocompatible chitosan materials

B Li, L Qiu, J Zhang, S Liu, M Xu, J Wang… - International Journal of …, 2024 - Elsevier
Chitosan has great potential for biomedical applications. However, the intractable solubility
of chitosan is a major bottleneck hampering its utilization. In this work, we report a low …

Molecular nature of ocular surface barrier function, diseases that affect it, and its relevance for ocular drug delivery

S Kaur, P Sohnen, S Swamynathan, Y Du, EM Espana… - The Ocular Surface, 2023 - Elsevier
The structural and functional integrity of the ocular surface, a continuous epithelial structure
comprised of the cornea, the conjunctiva, and the ductal surface of the lacrimal as well as …