Cushing's syndrome

A Lacroix, RA Feelders, CA Stratakis, LK Nieman - The lancet, 2015 - thelancet.com
Chronic exposure to excess glucorticoids results in diverse manifestations of Cushing's
syndrome, including debilitating morbidities and increased mortality. Genetic and molecular …

Clinical, pathophysiologic, genetic, and therapeutic progress in primary bilateral macronodular adrenal hyperplasia

J Bertherat, I Bourdeau, L Bouys… - Endocrine …, 2023 - academic.oup.com
Patients with primary bilateral macronodular adrenal hyperplasia (PBMAH) usually present
bilateral benign adrenocortical macronodules at imaging and variable levels of cortisol …

ARMC5 Mutations in Macronodular Adrenal Hyperplasia with Cushing's Syndrome

G Assié, R Libé, S Espiard, M Rizk-Rabin… - … England Journal of …, 2013 - Mass Medical Soc
Background Corticotropin-independent macronodular adrenal hyperplasia may be an
incidental finding or it may be identified during evaluation for Cushing's syndrome. Reports …

Intraadrenal corticotropin in bilateral macronodular adrenal hyperplasia

E Louiset, C Duparc, J Young, S Renouf… - … England Journal of …, 2013 - Mass Medical Soc
Background Bilateral macronodular adrenal hyperplasia is a rare cause of primary adrenal
Cushing's syndrome. In this form of hyperplasia, hypersecretion of cortisol suppresses the …

Wnt/β-catenin signalling in adrenal physiology and tumour development

A Berthon, A Martinez, J Bertherat, P Val - Molecular and cellular …, 2012 - Elsevier
Wnt/β-catenin signalling plays essential roles during embryonic development and in adult
tissue homeostasis. Canonical signalling through Wnt secreted ligands relies on the control …

Unilateral adrenalectomy as a first-line treatment of Cushing's syndrome in patients with primary bilateral macronodular adrenal hyperplasia

E Debillon, F Velayoudom-Cephise… - The Journal of …, 2015 - academic.oup.com
Context: Bilateral adrenalectomy is the reference treatment for Cushing's syndrome (CS)
related to primary bilateral macronodular adrenal hyperplasia (PBMAH). It is, however …

Diagnosis and management of primary bilateral macronodular adrenal hyperplasia

DA Vassiliadi, S Tsagarakis - Endocrine-Related Cancer, 2019 - erc.bioscientifica.com
Primary bilateral macronodular adrenal hyperplasia (PBMAH) is a highly heterogeneous
entity. The incidental identification of an increasing number of cases has shifted its clinical …

An analysis of different therapeutic options in patients with C ushing's syndrome due to bilateral macronodular adrenal hyperplasia: a single‐centre experience

NM Albiger, F Ceccato, M Zilio, M Barbot… - Clinical …, 2015 - Wiley Online Library
Context Bilateral macronodular adrenal hyperplasia (BMAH) is a rare form of Cushing's
syndrome (CS). A variety of in vivo tests to identify aberrant receptor expression have been …

Bilateral adrenal hyperplasia: pathogenesis and treatment

B Chevalier, MC Vantyghem, S Espiard - Biomedicines, 2021 - mdpi.com
Bilateral adrenal hyperplasia is a rare cause of Cushing's syndrome. Micronodular adrenal
hyperplasia, including the primary pigmented micronodular adrenal dysplasia (PPNAD) and …

Sexual dimorphism and thyroid dysfunction: a matter of oxidative stress?

RS Fortunato, ACF Ferreira, F Hecht… - Journal of …, 2014 - joe.bioscientifica.com
Testis development from an indifferent gonad is a critical step in embryogenesis. A hallmark
of testis differentiation is sex-specific vascularization that occurs as endothelial cells migrate …