Advances in oral drug delivery systems: Challenges and opportunities

J Lou, H Duan, Q Qin, Z Teng, F Gan, X Zhou, X Zhou - Pharmaceutics, 2023 - mdpi.com
The oral route is the most preferred route for systemic and local drug delivery. However, the
oral drug delivery system faces the harsh physiological and physicochemical environment of …

Electrospun nanofibres in drug delivery: advances in controlled release strategies

MK Gaydhane, CS Sharma, S Majumdar - RSC advances, 2023 - pubs.rsc.org
Emerging drug-delivery systems demand a controlled or programmable or sustained
release of drug molecules to improve therapeutic efficacy and patient compliance. Such …

Gastroretentive technologies in tandem with controlled-release strategies: A potent answer to oral drug bioavailability and patient compliance implications

NN Vrettos, CJ Roberts, Z Zhu - Pharmaceutics, 2021 - mdpi.com
There have been many efforts to improve oral drug bioavailability and therapeutic efficacy
and patient compliance. A variety of controlled-release oral delivery systems have been …

Electrospun nanofiber composites for drug delivery: A review on current progresses

R Jiffrin, SIA Razak, MI Jamaludin, ASA Hamzah… - Polymers, 2022 - mdpi.com
A medication's approximate release profile should be sustained in order to generate the
desired therapeutic effect. The drug's release site, duration, and rate must all be adjusted to …

Electrospinning nanofiber technology: a multifaceted paradigm in biomedical applications

A Garkal, D Kulkarni, S Musale, T Mehta… - New Journal of …, 2021 - pubs.rsc.org
Nanofibres are gaining significant popularity in biomedical applications. Advancement of
electrospinning setup and collector design has led to the use of nanofibers in biomedical …

Review of the principles, devices, parameters, and applications for centrifugal electrospinning

J Chen, Z Yu, C Li, Y Lv, S Hong… - Macromolecular …, 2022 - Wiley Online Library
Nanofibers have received extensive attention in the fields of biomedicine, energy catalysis,
environmental sciences, and filtration owing to their high specific surface area and …

A review on the applications of electrospun chitosan nanofibers for the cancer treatment

PG Shikhi-Abadi, M Irani - International Journal of Biological …, 2021 - Elsevier
In recent years, the incidence of cancer is increasing every day due to poor quality of life
(industrialization of life). Therefore, the treatment of cancer has received much attention from …

pH-sensitive bilayer electrospun nanofibers based on ethyl cellulose and Eudragit S-100 as a dual delivery system for treatment of the burn wounds; preparation …

M Amani, A Rakhshani, S Maghsoudian… - International Journal of …, 2023 - Elsevier
A pH-sensitive bilayer electrospun nanofibrous mat containing both antibiotic (gentamicin
sulfate, GEN) and non-steroidal anti-inflammatory (diclofenac sodium, DIC) drugs was …

Pilot study of cytoprotective mechanisms of selenium nanorods (SeNrs) under ischemia-like conditions on cortical astrocytes

EG Varlamova, EY Plotnikov, IV Baimler… - International Journal of …, 2023 - mdpi.com
The cytoprotective properties of the trace element selenium, its nanoparticles, and selenium
nanocomplexes with active compounds are shown using a number of models. To date …

An overview of nanofibers and microfibers for improved oral delivery of medicines: Challenges and advances

P Ghasemiyeh, S Mohammadi-Samani… - Journal of Drug Delivery …, 2024 - Elsevier
Nanofibers and microfibers are polymer-based drug delivery systems commonly fabricated
through the electrospinning technique. They can be fabricated using natural, synthetic, or …