Colorectal liver metastasis: molecular mechanism and interventional therapy
H Zhou, Z Liu, Y Wang, X Wen, EH Amador… - Signal transduction and …, 2022 - nature.com
Colorectal cancer (CRC) is one of the most frequently occurring malignancy tumors with a
high morbidity additionally, CRC patients may develop liver metastasis, which is the major …
high morbidity additionally, CRC patients may develop liver metastasis, which is the major …
miRNAs as cornerstones in colorectal cancer pathogenesis and resistance to therapy: A spotlight on signaling pathways interplay—A review
MA Elrebehy, S Al-Saeed, S Gamal, A El-Sayed… - International journal of …, 2022 - Elsevier
Colorectal cancer (CRC) is the world's third most prevalent cancer and the main cause of
cancer-related mortality. A lot of work has been put into improving CRC patients' clinical …
cancer-related mortality. A lot of work has been put into improving CRC patients' clinical …
The lncRNA CRNDE promotes colorectal cancer cell proliferation and chemoresistance via miR-181a-5p-mediated regulation of Wnt/β-catenin signaling
P Han, J Li, B Zhang, J Lv, Y Li, X Gu, Z Yu, Y Jia, X Bai… - Molecular cancer, 2017 - Springer
Background With more than 600,000 mortalities each year, colorectal cancer (CRC) is the
third most commonly diagnosed type of cancer worldwide. Recently, mechanisms involving …
third most commonly diagnosed type of cancer worldwide. Recently, mechanisms involving …
[HTML][HTML] The role of miRNAs in colorectal cancer progression and chemoradiotherapy
Colorectal cancer (CRC) is known as the third most common cancer as well as the fourth
most deadly cancer worldwide. CRC accounts for approximately 10% of all new cancer …
most deadly cancer worldwide. CRC accounts for approximately 10% of all new cancer …
The pervasive role of the miR-181 family in development, neurodegeneration, and cancer
MicroRNAs (miRNAs) are small noncoding RNAs playing a fundamental role in the
regulation of gene expression. Evidence accumulating in the past decades indicate that they …
regulation of gene expression. Evidence accumulating in the past decades indicate that they …
MicroRNAs: Potential candidates for diagnosis and treatment of colorectal cancer
A Moridikia, H Mirzaei, A Sahebkar… - Journal of cellular …, 2018 - Wiley Online Library
Colorectal cancer (CRC) is known as the third common cancer worldwide and an important
public health problem in different populations. Several genetics and environmental risk …
public health problem in different populations. Several genetics and environmental risk …
miR-181a-5p inhibits cancer cell migration and angiogenesis via downregulation of matrix metalloproteinase-14
Y Li, C Kuscu, A Banach, Q Zhang, A Pulkoski-Gross… - Cancer research, 2015 - AACR
Upregulation of matrix metalloproteinase MMP-14 (MT1-MMP) is associated with poor
prognosis in cancer patients, but it is unclear how MMP-14 becomes elevated in tumors …
prognosis in cancer patients, but it is unclear how MMP-14 becomes elevated in tumors …
[HTML][HTML] Effects of mutations in Wnt/β-catenin, hedgehog, Notch and PI3K pathways on GSK-3 activity—Diverse effects on cell growth, metabolism and cancer
JA McCubrey, D Rakus, A Gizak, LS Steelman… - … et Biophysica Acta (BBA …, 2016 - Elsevier
Abstract Glycogen synthase kinase-3 (GSK-3) is a serine/threonine kinase that participates
in an array of critical cellular processes. GSK-3 was first characterized as an enzyme that …
in an array of critical cellular processes. GSK-3 was first characterized as an enzyme that …
sChemNET: a deep learning framework for predicting small molecules targeting microRNA function
MicroRNAs (miRNAs) have been implicated in human disorders, from cancers to infectious
diseases. Targeting miRNAs or their target genes with small molecules offers opportunities …
diseases. Targeting miRNAs or their target genes with small molecules offers opportunities …
[HTML][HTML] Exosome-mediated miRNA delivery promotes liver cancer EMT and metastasis
Q Lin, CR Zhou, MJ Bai, D Zhu, JW Chen… - American journal of …, 2020 - ncbi.nlm.nih.gov
The deregulation of exosomal microRNAs (miRNAs) plays an important role in the
progression of hepatocarcinogenesis. In this study, we highlight exosomes as mediators …
progression of hepatocarcinogenesis. In this study, we highlight exosomes as mediators …