Dizygotic twinning

C Hoekstra, ZZ Zhao, CB Lambalk… - Human reproduction …, 2008 - academic.oup.com
The tendency to conceive spontaneous dizygotic (DZ) twins is a complex trait with important
contributions from both environmental factors and genetic disposition. Twins are relatively …

Meta-analysis of twin studies highlights the importance of genetic variation in primary school educational achievement

EL de Zeeuw, EJC de Geus, DI Boomsma - Trends in Neuroscience and …, 2015 - Elsevier
Children differ in their ability to learn what is taught at school. Evidence from twin studies
suggests that genetic effects contribute to such differences. The aim of the present study was …

Meta-analysis of genome-wide association studies of anxiety disorders

T Otowa, K Hek, M Lee, EM Byrne, SS Mirza… - Molecular …, 2016 - nature.com
Anxiety disorders (ADs), namely generalized AD, panic disorder and phobias, are common,
etiologically complex conditions with a partially genetic basis. Despite differing on diagnostic …

Disease variants alter transcription factor levels and methylation of their binding sites

MJ Bonder, R Luijk, DV Zhernakova, M Moed… - Nature …, 2017 - nature.com
Most disease-associated genetic variants are noncoding, making it challenging to design
experiments to understand their functional consequences,. Identification of expression …

The Netherlands twin register: longitudinal research based on twin and twin-family designs

L Ligthart, CEM van Beijsterveldt… - Twin Research and …, 2019 - cambridge.org
The Netherlands Twin Register (NTR) is a national register in which twins, multiples and
their parents, siblings, spouses and other family members participate. Here we describe the …

Meta-analysis of genome-wide association studies in> 80 000 subjects identifies multiple loci for C-reactive protein levels

A Dehghan, J Dupuis, M Barbalic, JC Bis… - Circulation, 2011 - Am Heart Assoc
Background—C-reactive protein (CRP) is a heritable marker of chronic inflammation that is
strongly associated with cardiovascular disease. We sought to identify genetic variants that …

Regular exercise, anxiety, depression and personality: a population-based study

MHM De Moor, AL Beem, JH Stubbe, DI Boomsma… - Preventive …, 2006 - Elsevier
OBJECTIVES: To examine whether regular exercise is associated with anxiety, depression
and personality in a large population-based sample as a function of gender and age …

Heritability of polycystic ovary syndrome in a Dutch twin-family study

JM Vink, S Sadrzadeh, CB Lambalk… - The Journal of Clinical …, 2006 - academic.oup.com
Background: Polycystic ovary syndrome (PCOS) is one of the most common endocrine
disorders among women of reproductive age. There is evidence for a genetic component in …

Heritability of adult body height: a comparative study of twin cohorts in eight countries

K Silventoinen, S Sammalisto, M Perola… - Twin Research and …, 2003 - cambridge.org
Amajor component of variation in body height is due to genetic differences, but
environmental factors have a substantial contributory effect. In this study we aimed to …

Age-related changes in heritability of behavioral phenotypes over adolescence and young adulthood: a meta-analysis

SE Bergen, CO Gardner, KS Kendler - Twin Research and Human …, 2007 - cambridge.org
The relative proportions of genetic and environmental variance in behavioral measures
have been studied extensively. A growing body of literature has examined changes in …