Monodentately-coordinated bioactive moieties in multimodal half-sandwich organoruthenium anticancer agents
Metallodrugs have a central role in the treatment and diagnosis of diseases. To overcome
potential toxicity and equip metal-based anticancer agents with biological activity, the choice …
potential toxicity and equip metal-based anticancer agents with biological activity, the choice …
Potential of CDC25 phosphatases in cancer research and treatment: key to precision medicine
I Dakilah, A Harb, E Abu-Gharbieh… - Frontiers in …, 2024 - frontiersin.org
The global burden of cancer continues to rise, underscoring the urgency of developing more
effective and precisely targeted therapies. This comprehensive review explores the …
effective and precisely targeted therapies. This comprehensive review explores the …
Suppressing glucose metabolism with epigallocatechin-3-gallate (EGCG) reduces breast cancer cell growth in preclinical models
R Wei, L Mao, P Xu, X Zheng, RM Hackman… - Food & function, 2018 - pubs.rsc.org
Numerous studies propose that epigallocatechin-3-gallate (EGCG), an abundant polyphenol
in green tea, has anti-cancer properties. However, its mechanism of action in breast cancer …
in green tea, has anti-cancer properties. However, its mechanism of action in breast cancer …
PD-1+ mast cell enhanced by PD-1 blocking therapy associated with resistance to immunotherapy
J Li, G Peng, K Zhu, X Jie, Y Xu, X Rao, Y Xu… - Cancer Immunology …, 2023 - Springer
Background Programmed cell death protein 1 (PD-1) antibody has been approved for a
variety of tumors, but its effective rate is unsatisfactory. New evidence suggests that mast …
variety of tumors, but its effective rate is unsatisfactory. New evidence suggests that mast …
[PDF][PDF] Nomogram for individualized prediction of hepatocellular carcinoma occurrence in hepatitis C virus cirrhosis (ANRS CO12 CirVir)
N Ganne‐Carrié, R Layese, V Bourcier, C Cagnot… - …, 2016 - Wiley Online Library
The aim of this work was to develop an individualized score for predicting hepatocellular
carcinoma (HCC) in patients with hepatitis C (HCV)‐compensated cirrhosis. Among 1,323 …
carcinoma (HCC) in patients with hepatitis C (HCV)‐compensated cirrhosis. Among 1,323 …
[PDF][PDF] Inhibition of mast cell‐secreted histamine decreases biliary proliferation and fibrosis in primary sclerosing cholangitis Mdr2−/− mice
H Jones, L Hargrove, L Kennedy, F Meng… - …, 2016 - Wiley Online Library
Hepatic fibrosis is marked by activation of hepatic stellate cells (HSCs). Cholestatic injury
precedes liver fibrosis, and cholangiocytes interact with HSCs promoting fibrosis. Mast cells …
precedes liver fibrosis, and cholangiocytes interact with HSCs promoting fibrosis. Mast cells …
[HTML][HTML] Hyaluronic acid (HA)-coated naproxen-nanoparticles selectively target breast cancer stem cells through COX-independent pathways
E Espinosa-Cano, M Huerta-Madronal… - Materials Science and …, 2021 - Elsevier
Cytotoxic chemotherapy continues to be the main therapeutic option for patients with
metastatic breast cancer. Several studies have reported a significant association between …
metastatic breast cancer. Several studies have reported a significant association between …
[HTML][HTML] Mast cell-T cell axis alters development of colitis-dependent and colitis-independent colorectal tumours: potential for therapeutically targeting via mast cell …
Background Colorectal cancer (CRC) has a high mortality rate and can develop in either
colitis-dependent (colitis-associated (CA)-CRC) or colitis-independent (sporadic (s) CRC) …
colitis-dependent (colitis-associated (CA)-CRC) or colitis-independent (sporadic (s) CRC) …
Reduction-responsive polypeptide nanogel delivers antitumor drug for improved efficacy and safety
K Huang, B Shi, W Xu, J Ding, Y Yang, H Liu… - Acta Biomaterialia, 2015 - Elsevier
Chemotherapy plays an irreplaceable role in the treatment of various malignant tumors
today. The traditional drug formulations lack of selectivity, cause serious damage to normal …
today. The traditional drug formulations lack of selectivity, cause serious damage to normal …
Secondary Metabolites Profiling, Antimicrobial and Cytotoxic Properties of Commiphora gileadensis L. Leaves, Seeds, Callus, and Cell Suspension Extracts
Commiphora gileadensis L. is an important endangered medicinal plant that belongs to the
family Burseraceae. In this study, C. gileadensis callus culture was established successfully …
family Burseraceae. In this study, C. gileadensis callus culture was established successfully …