Micro RNAs (miRNAs) are a class of small non-coding RNAs that have a crucial role in
cellular processes such as differentiation, proliferation, migration, and apoptosis. miRNAs …

Chronic myeloid leukemia (CML) is a classical example of stem cell cancer since it arises in
a multipotent hematopoietic stem cell upon the acquisition of the t (9; 22) chromosomal …

The therapeutic landscape for chronic myeloid leukemia (CML) has improved significantly
with the approval of tyrosine kinase inhibitors (TKIs) for therapeutic use. Most patients with …

Chronic myeloid leukemia (CML) is a myeloproliferative neoplasm generated by reciprocal
chromosomal translocation, t (9; 22)(q34; q11) in the transformed hematopoietic stem cell …

Notoriously known for their capacity to reconstitute hematological malignancies in vivo,
leukemic stem cells (LSCs) represent key drivers of therapeutic resistance and disease …

Simple Summary CD26/dipeptidylpeptidase IV (DPP-4) is a membrane-bound
multifunctional protein expressed in many primary solid tumors and in hematological …

Many tumours are organised in a hierarchical structure with at its apex a cell that can
maintain, establish, and repopulate the tumour—the cancer stem cell. The haematopoietic …

MicroRNA: From Bench to Bedside provides an in-depth, expansive overview of microRNA
from fundamentals to clinical practice. It presents researchers with detailed insights on the …

Introduction MicroRNAs may be implicated in the acquisition of drug resistance in chronic
myeloid leukemia as they regulate the expression of not only BCR-ABL1 but also genes …

Leukemia as one of the common cancers is still studied and needs improvement in
diagnosis and treatment. In this study, we examined the activity of hematopoietic stem cells …