Ruminococcus gnavus: friend or foe for human health

EH Crost, E Coletto, A Bell… - FEMS Microbiology …, 2023 - academic.oup.com
Ruminococcus gnavus was first identified in 1974 as a strict anaerobe in the gut of healthy
individuals, and for several decades, its study has been limited to specific enzymes or …

Mechanism of action of ribosomally synthesized and post-translationally modified peptides

C Ongpipattanakul, EK Desormeaux… - Chemical …, 2022 - ACS Publications
Ribosomally synthesized and post-translationally modified peptides (RiPPs) are a natural
product class that has undergone significant expansion due to the rapid growth in genome …

[HTML][HTML] The microbiome-shaping roles of bacteriocins

S Heilbronner, B Krismer, H Brötz-Oesterhelt… - Nature Reviews …, 2021 - nature.com
The microbiomes on human body surfaces affect health in multiple ways. They include not
only commensal or mutualistic bacteria but also potentially pathogenic bacteria, which can …

Bacteriocins as a new generation of antimicrobials: toxicity aspects and regulations

S Soltani, R Hammami, PD Cotter… - FEMS microbiology …, 2021 - academic.oup.com
In recent decades, bacteriocins have received substantial attention as antimicrobial
compounds. Although bacteriocins have been predominantly exploited as food …

The mechanisms and the applications of antibacterial polymers in surface modification on medical devices

H Qiu, Z Si, Y Luo, P Feng, X Wu, W Hou… - … in bioengineering and …, 2020 - frontiersin.org
Medical device contamination caused by microbial pathogens such as bacteria and fungi
has posed a severe threat to the patients' health in hospitals. Due to the increasing …

Probiotics, prebiotics, and postbiotics in health and disease

J Ji, W Jin, SJ Liu, Z Jiao, X Li - MedComm, 2023 - Wiley Online Library
The gut microbiota and its homeostasis play a crucial role in human health. However, for
some diseases related to the gut microbiota, current traditional medicines can only relieve …

Bacteriocins: potential for human health

F Huang, K Teng, Y Liu, Y Cao, T Wang… - Oxidative medicine …, 2021 - Wiley Online Library
Due to the challenges of antibiotic resistance to global health, bacteriocins as antimicrobial
compounds have received more and more attention. Bacteriocins are biosynthesized by …

Overview of global trends in classification, methods of preparation and application of bacteriocins

M Zimina, O Babich, A Prosekov, S Sukhikh, S Ivanova… - Antibiotics, 2020 - mdpi.com
This paper summarizes information about the division of bacteriocins into classes (Gram-
negative bacteria, Gram-positive bacteria, and archaea). Methods for producing bacteriocins …

Radical SAM-dependent ether crosslink in daropeptide biosynthesis

S Guo, S Wang, S Ma, Z Deng, W Ding… - Nature …, 2022 - nature.com
Darobactin is a ribosomally synthesized and post-translationally modified peptide (RiPP),
which possesses potent activity against various Gram-negative bacteria. Darobactin features …

The manifold roles of microbial ribosomal peptide–based natural products in physiology and ecology

Y Li, S Rebuffat - Journal of Biological Chemistry, 2020 - ASBMB
The ribosomally synthesized and posttranslationally modified peptides (RiPPs), also called
ribosomal peptide natural products (RPNPs), form a growing superfamily of natural products …