Cellular mechanisms of melatonin: insight from neurodegenerative diseases

D Chen, T Zhang, TH Lee - Biomolecules, 2020 - mdpi.com
Neurodegenerative diseases are the second most common cause of death and
characterized by progressive impairments in movement or mental functioning in the central …

Molecular mechanisms of vascular dementia: what can be learned from animal models of chronic cerebral hypoperfusion?

SQ Du, XR Wang, LY Xiao, JF Tu, W Zhu, T He… - Molecular …, 2017 - Springer
Vascular dementia (VD) is defined as a progressive neurodegenerative disease of cognitive
decline, attributable to cerebrovascular factors. Numerous studies have demonstrated that …

[PDF][PDF] Vitamin D and neurodegenerative diseases

W Wang, Y Li, X Meng - Heliyon, 2023 - cell.com
Neurodegenerative diseases, featured by progressive loss of structure or function of
neurons, are considered incurable at present. Movement disorders like tremor and postural …

[HTML][HTML] Vinpocetine reduces diclofenac-induced acute kidney injury through inhibition of oxidative stress, apoptosis, cytokine production, and NF-κB activation in mice

V Fattori, SM Borghi, CFS Guazelli, AC Giroldo… - Pharmacological …, 2017 - Elsevier
Acute kidney injury (AKI) represents a complex clinical condition associated with significant
morbidity and mortality. Approximately, 19–33% AKI episodes in hospitalized patients are …

The neuroprotective effect of curcumin against Cd-induced neurotoxicity and hippocampal neurogenesis promotion through CREB-BDNF signaling pathway

D Namgyal, S Ali, R Mehta, M Sarwat - Toxicology, 2020 - Elsevier
Heavy metal neurotoxicity is one of the major challenges in today's era due to the large
scale and widespread mechanisation of the production. However, the causative factors …

Citrate‐coated silver nanoparticles loaded with agomelatine provide neuronal therapy in acute cerebral ischemia/reperfusion of rats by inhibiting the oxidative stress …

V Gelen, S Özkanlar, A Kara… - Environmental …, 2024 - Wiley Online Library
Cerebral ischemia and reperfusion are related to various situations like injuries after various
traumas, oxidative stress, increased calcium ion, capillary hypoperfusion, microvascular …

Vinpocetine amended prenatal valproic acid induced features of ASD possibly by altering markers of neuronal function, inflammation, and oxidative stress

K Luhach, GT Kulkarni, VP Singh, B Sharma - Autism Research, 2021 - Wiley Online Library
Autism spectrum disorder (ASD) is a neurodevelopmental disorder with complex etiology
and phenotypes. Phosphodiesterase‐1 (PDE1) inhibitors are known to provide benefits in …

Agomelatine: a potential novel approach for the treatment of memory disorder in neurodegenerative disease

Q Su, T Li, GW Liu, YL Zhang, JH Guo… - Neural Regeneration …, 2023 - journals.lww.com
Agomelatine is a selective agonist of melatonin receptor 1A/melatonin receptor 1B (MT 1/MT
2) and antagonist of 5-hydroxytryptamine 2C receptors. It is used clinically to treat major …

Agomelatine confers neuroprotection against cisplatin-induced hippocampal neurotoxicity

FN Cankara, C Günaydın, ZB Çelik, Y Şahin… - Metabolic brain …, 2021 - Springer
Neurotoxicity caused by cisplatin is a major obstacle during chemotherapy. Oxidative stress
and inflammation are considered the primary mechanism behind neuronal damage which …

Dim light at night induced neurodegeneration and ameliorative effect of curcumin

D Namgyal, K Chandan, A Sultan, M Aftab, S Ali… - Cells, 2020 - mdpi.com
It is a well-known fact that following a proper routine light/dark or diurnal rhythm controls
almost all biological processes. With the introduction of modern lighting and artificial …