Portable biosensing devices for point-of-care diagnostics: Recent developments and applications

M Zarei - TrAC Trends in Analytical Chemistry, 2017 - Elsevier
Low-cost point-of-care (POC) diagnostics play several critical roles in healthcare strategies,
particularly for detection, therapy, economy, health management, and surveillance. Any user …

Point-of-care testing: applications of 3D printing

HN Chan, MJA Tan, H Wu - Lab on a Chip, 2017 - pubs.rsc.org
Point-of-care testing (POCT) devices fulfil a critical need in the modern healthcare
ecosystem, enabling the decentralized delivery of imperative clinical strategies in both …

Ultrasensitive single extracellular vesicle detection using high throughput droplet digital enzyme-linked immunosorbent assay

Z Yang, Y Atiyas, H Shen, MJ Siedlik, J Wu, K Beard… - Nano …, 2022 - ACS Publications
Extracellular vesicles (EVs) have attracted enormous attention for their diagnostic and
therapeutic potential. However, it has proven challenging to achieve the sensitivity to detect …

Mobile platform for rapid sub–picogram-per-milliliter, multiplexed, digital droplet detection of proteins

V Yelleswarapu, JR Buser, M Haber… - Proceedings of the …, 2019 - National Acad Sciences
Digital droplet assays—in which biological samples are compartmentalized into millions of
femtoliter-volume droplets and interrogated individually—have generated enormous …

Smartphone-based fluorescent lateral flow immunoassay platform for highly sensitive point-of-care detection of Zika virus nonstructural protein 1

Z Rong, Q Wang, N Sun, X Jia, K Wang, R Xiao… - Analytica chimica …, 2019 - Elsevier
Simple, inexpensive, and rapid diagnostic tests in low-resource settings with limited
laboratory equipment and technical expertise are instrumental in reducing morbidity and …

Interfacing pathogen detection with smartphones for point-of-care applications

X Ding, MG Mauk, K Yin, K Kadimisetty… - Analytical chemistry, 2018 - ACS Publications
Infectious diseases are clinically relevant, transmissible illnesses caused by
microorganisms, such as bacteria, viruses, fungi, and parasites. According to a recent report …

Microfluidics for antibiotic susceptibility testing

W Postek, N Pacocha, P Garstecki - Lab on a Chip, 2022 - pubs.rsc.org
The rise of antibiotic resistance is a threat to global health. Rapid and comprehensive
analysis of infectious strains is critical to reducing the global use of antibiotics, as informed …

Rapid bacterial detection and antibiotic susceptibility testing in whole blood using one-step, high throughput blood digital PCR

TJ Abram, H Cherukury, CY Ou, T Vu, M Toledano… - Lab on a Chip, 2020 - pubs.rsc.org
Sepsis due to antimicrobial resistant pathogens is a major health problem worldwide. The
inability to rapidly detect and thus treat bacteria with appropriate agents in the early stages …

Machine learning to detect signatures of disease in liquid biopsies–a user's guide

J Ko, SN Baldassano, PL Loh, K Kording, B Litt… - Lab on a Chip, 2018 - pubs.rsc.org
New technologies that measure sparse molecular biomarkers from easily accessible bodily
fluids (eg blood, urine, and saliva) are revolutionizing disease diagnostics and precision …

“Development and application of analytical detection techniques for droplet-based microfluidics”-A review

W Liu, Y Zhu - Analytica Chimica Acta, 2020 - Elsevier
Droplet-based microfluidics has emerged as a powerful platform for high-throughput and low-
volume analysis and screening. At present, droplet-based microfluidics is transitioning from …