Neuroimaging standards for research into small vessel disease—advances since 2013

M Duering, GJ Biessels, A Brodtmann, C Chen… - The Lancet …, 2023 - thelancet.com
Cerebral small vessel disease (SVD) is common during ageing and can present as stroke,
cognitive decline, neurobehavioural symptoms, or functional impairment. SVD frequently …

Perivascular spaces in the brain: anatomy, physiology and pathology

JM Wardlaw, H Benveniste, M Nedergaard… - Nature Reviews …, 2020 - nature.com
Perivascular spaces include a variety of passageways around arterioles, capillaries and
venules in the brain, along which a range of substances can move. Although perivascular …

[HTML][HTML] Vascular cognitive impairment (VCI)

T Rundek, M Tolea, T Ariko, EA Fagerli, CJ Camargo - Neurotherapeutics, 2023 - Elsevier
Vascular cognitive impairment (VCI) is predominately caused by vascular risk factors and
cerebrovascular disease. VCI includes a broad spectrum of cognitive disorders, from mild …

Update on cerebral small vessel disease: a dynamic whole-brain disease

Y Shi, JM Wardlaw - Stroke and vascular neurology, 2016 - svn.bmj.com
Cerebral small vessel disease (CSVD) is a very common neurological disease in older
people. It causes stroke and dementia, mood disturbance and gait problems. Since it is …

Perivascular spaces, glymphatic dysfunction, and small vessel disease

H Mestre, S Kostrikov, RI Mehta… - Clinical …, 2017 - portlandpress.com
Cerebral small vessel diseases (SVDs) range broadly in etiology but share remarkably
overlapping pathology. Features of SVD including enlarged perivascular spaces (EPVS) …

Perivascular space dilation is associated with vascular amyloid-β accumulation in the overlying cortex

V Perosa, J Oltmer, LP Munting, WM Freeze… - Acta …, 2022 - Springer
Perivascular spaces (PVS) are compartments surrounding cerebral blood vessels that
become visible on MRI when enlarged. Enlarged PVS (EPVS) are commonly seen in …

Perivascular spaces and brain waste clearance systems: relevance for neurodegenerative and cerebrovascular pathology

K Gouveia-Freitas, AJ Bastos-Leite - Neuroradiology, 2021 - Springer
Perivascular spaces (PVS) of the brain, often called Virchow-Robin spaces, comprise fluid,
cells and connective tissue, and are externally limited by astrocytic endfeet. PVS are …

The association between glymphatic system dysfunction and cognitive impairment in cerebral small vessel disease

J Tang, M Zhang, N Liu, Y Xue, X Ren… - Frontiers in aging …, 2022 - frontiersin.org
The mechanism of cognitive impairment in patients with cerebral small vessel disease
(CSVD) remains unknown. The glymphatic system dysfunction, which has been …

Perivascular spaces and their associations with risk factors, clinical disorders and neuroimaging features: a systematic review and meta-analysis

F Francis, L Ballerini… - International Journal of …, 2019 - journals.sagepub.com
Background Perivascular spaces, visible on brain magnetic resonance imaging, are thought
to be associated with small vessel disease, neuroinflammation, and to be important for …

Total small vessel disease score and risk of recurrent stroke: validation in 2 large cohorts

KK Lau, L Li, U Schulz, M Simoni, KH Chan, SL Ho… - Neurology, 2017 - AAN Enterprises
Objective: In patients with TIA and ischemic stroke, we validated the total small vessel
disease (SVD) score by determining its prognostic value for recurrent stroke. Methods: Two …