The oral microbiome: diversity, biogeography and human health

JL Baker, JL Mark Welch, KM Kauffman… - Nature Reviews …, 2024 - nature.com
The human oral microbiota is highly diverse and has a complex ecology, comprising
bacteria, microeukaryotes, archaea and viruses. These communities have elaborate and …

Gut–liver axis: barriers and functional circuits

O Pabst, MW Hornef, FG Schaap, V Cerovic… - Nature Reviews …, 2023 - nature.com
The gut and the liver are characterized by mutual interactions between both organs, the
microbiome, diet and other environmental factors. The sum of these interactions is …

Major data analysis errors invalidate cancer microbiome findings

A Gihawi, Y Ge, J Lu, D Puiu, A Xu, CS Cooper… - MBio, 2023 - Am Soc Microbiol
We re-analyzed the data from a recent large-scale study that reported strong correlations
between DNA signatures of microbial organisms and 33 different cancer types and that …

Utilization of the microbiome in personalized medicine

K Ratiner, D Ciocan, SK Abdeen, E Elinav - Nature Reviews …, 2024 - nature.com
Inter-individual human variability, driven by various genetic and environmental factors,
complicates the ability to develop effective population-based early disease detection …

The maternal gut microbiome in pregnancy: implications for the developing immune system

O Koren, L Konnikova, P Brodin, IU Mysorekar… - Nature Reviews …, 2024 - nature.com
The gut microbiome has important roles in host metabolism and immunity, and microbial
dysbiosis affects human physiology and health. Maternal immunity and microbial …

Gastrointestinal and brain barriers: unlocking gates of communication across the microbiota–gut–brain axis

MR Aburto, JF Cryan - Nature Reviews Gastroenterology & Hepatology, 2024 - nature.com
Crosstalk between gut and brain has long been appreciated in health and disease, and the
gut microbiota is a key player in communication between these two distant organs. Yet, the …

Intracellular bacteria in cancer—Prospects and debates

L Schorr, M Mathies, E Elinav, J Puschhof - npj Biofilms and …, 2023 - nature.com
Recent evidence suggests that some human cancers may harbor low-biomass microbial
ecosystems, spanning bacteria, viruses, and fungi. Bacteria, the most-studied kingdom in …

The placenta: a maternofetal interface

K O'Brien, Y Wang - Annual Review of Nutrition, 2023 - annualreviews.org
The placenta is the gatekeeper between the mother and the fetus. Over the first trimester of
pregnancy, the fetus is nourished by uterine gland secretions in a process known as …

The blood microbiome and health: current evidence, controversies, and challenges

HS Cheng, SP Tan, DMK Wong, WLY Koo… - International Journal of …, 2023 - mdpi.com
Blood is conventionally thought to be sterile. However, emerging evidence on the blood
microbiome has started to challenge this notion. Recent reports have revealed the presence …

The intersection of undernutrition, microbiome, and child development in the first years of life

F Fontaine, S Turjeman, K Callens, O Koren - Nature Communications, 2023 - nature.com
Undernutrition affects about one out of five children worldwide. It is associated with impaired
growth, neurodevelopment deficits, and increased infectious morbidity and mortality …