Background Pickling, as an ancient culinary technique (predate to 2400 BCE), protected
food in brine and/or sugar, which caused metabolites to undergo a series of chemical …

Multiclass metabolomic studies have become popular for revealing the differences in
multiple stages of complex diseases, various lifestyles, or the effects of specific treatments. In …

The development of ion mobility–mass spectrometry (IM–MS) has revolutionized the
analysis of small molecules, such as metabolomics, lipidomics, and exposome studies. The …

Bile acids regulate nutrient absorption and mitochondrial function, they establish and
maintain gut microbial community composition and mediate inflammation, and they serve as …

Spatial lipidomics based on mass spectrometry imaging (MSI) is a powerful tool for
fundamental biology studies and biomarker discovery. But the structure‐resolving capability …

Omics studies such as metabolomics, lipidomics, and proteomics have become important for
understanding the mechanisms in living organisms. However, the compounds detected are …

Ion mobility spectrometry‐mass spectrometry (IMS‐MS or IM‐MS) is a powerful analytical
technique that combines the gas‐phase separation capabilities of IM with the identification …

Libraries of collision cross-section (CCS) values have the potential to facilitate compound
identification in metabolomics. Although computational methods provide an opportunity to …

Per-and polyfluoroalkyl substances (PFAS) remain controversial due to their high
persistency and potential human toxicity. Although occupational exposure to PFAS has been …

In addition to providing critical knowledge of the accurate mass of ions, ion mobility‐mass
spectrometry (IM‐MS) delivers complementary data relating to the conformation and size of …