[HTML][HTML] The world of protein acetylation
Acetylation is one of the major post-translational protein modifications in the cell, with
manifold effects on the protein level as well as on the metabolome level. The acetyl group …
manifold effects on the protein level as well as on the metabolome level. The acetyl group …
Escherichia coli as a host for metabolic engineering
Over the past century, Escherichia coli has become one of the best studied organisms on
earth. Features such as genetic tractability, favorable growth conditions, well characterized …
earth. Features such as genetic tractability, favorable growth conditions, well characterized …
The quantitative and condition-dependent Escherichia coli proteome
Measuring precise concentrations of proteins can provide insights into biological processes.
Here we use efficient protein extraction and sample fractionation, as well as state-of-the-art …
Here we use efficient protein extraction and sample fractionation, as well as state-of-the-art …
The growing landscape of lysine acetylation links metabolism and cell signalling
Lysine acetylation is a conserved protein post-translational modification that links acetyl-
coenzyme A metabolism and cellular signalling. Recent advances in the identification and …
coenzyme A metabolism and cellular signalling. Recent advances in the identification and …
SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways
Protein function is regulated by diverse posttranslational modifications. The mitochondrial
sirtuin SIRT5 removes malonyl and succinyl moieties from target lysines. The spectrum of …
sirtuin SIRT5 removes malonyl and succinyl moieties from target lysines. The spectrum of …
Metabolic regulation by lysine malonylation, succinylation, and glutarylation
MD Hirschey, Y Zhao - Molecular & Cellular Proteomics, 2015 - ASBMB
Protein acetylation is a well-studied regulatory mechanism for several cellular processes,
ranging from gene expression to metabolism. Recent discoveries of new post-translational …
ranging from gene expression to metabolism. Recent discoveries of new post-translational …
Regulation of cellular metabolism by protein lysine acetylation
Protein lysine acetylation has emerged as a key posttranslational modification in cellular
regulation, in particular through the modification of histones and nuclear transcription …
regulation, in particular through the modification of histones and nuclear transcription …
Post-translational protein acetylation: an elegant mechanism for bacteria to dynamically regulate metabolic functions
Post-translational modifications (PTM) decorate proteins to provide functional heterogeneity
to an existing proteome. The large number of known PTMs highlights the many ways that …
to an existing proteome. The large number of known PTMs highlights the many ways that …
Identification of lysine succinylation as a new post-translational modification
Of the 20 ribosomally coded amino acid residues, lysine is the most frequently post-
translationally modified, which has important functional and regulatory consequences. Here …
translationally modified, which has important functional and regulatory consequences. Here …
Acetate revisited: A key biomolecule at the nexus of metabolism, epigenetics and oncogenesis—Part 1: Acetyl-CoA, acetogenesis and acyl-CoA short-chain …
JR Moffett, N Puthillathu, R Vengilote… - Frontiers in …, 2020 - frontiersin.org
Acetate is a major end product of bacterial fermentation of fiber in the gut. Acetate, whether
derived from the diet or from fermentation in the colon, has been implicated in a range of …
derived from the diet or from fermentation in the colon, has been implicated in a range of …