[HTML][HTML] Imaging neurotransmitter and neuromodulator dynamics in vivo with genetically encoded indicators

BL Sabatini, L Tian - Neuron, 2020 - cell.com
The actions of neuromodulation are thought to mediate the ability of the mammalian brain to
dynamically adjust its functional state in response to changes in the environment. Altered …

[HTML][HTML] Astroglial glutamate signaling and uptake in the hippocampus

CR Rose, L Felix, A Zeug, D Dietrich… - Frontiers in Molecular …, 2018 - frontiersin.org
Astrocytes have long been regarded as essentially unexcitable cells that do not contribute to
active signaling and information processing in the brain. Contrary to this classical view, it is …

A positively tuned voltage indicator for extended electrical recordings in the brain

SW Evans, DQ Shi, M Chavarha, MH Plitt, J Taxidis… - Nature …, 2023 - nature.com
Genetically encoded voltage indicators (GEVIs) enable optical recording of electrical signals
in the brain, providing subthreshold sensitivity and temporal resolution not possible with …

[HTML][HTML] Sustained deep-tissue voltage recording using a fast indicator evolved for two-photon microscopy

Z Liu, X Lu, V Villette, Y Gou, KL Colbert, S Lai, S Guan… - Cell, 2022 - cell.com
Genetically encoded voltage indicators are emerging tools for monitoring voltage dynamics
with cell-type specificity. However, current indicators enable a narrow range of applications …

Dual-polarity voltage imaging of the concurrent dynamics of multiple neuron types

M Kannan, G Vasan, S Haziza, C Huang… - Science, 2022 - science.org
Genetically encoded fluorescent voltage indicators are ideally suited to reveal the
millisecond-scale interactions among and between targeted cell populations. However …

[HTML][HTML] Fast two-photon imaging of subcellular voltage dynamics in neuronal tissue with genetically encoded indicators

S Chamberland, HH Yang, MM Pan, SW Evans… - elife, 2017 - elifesciences.org
Monitoring voltage dynamics in defined neurons deep in the brain is critical for unraveling
the function of neuronal circuits but is challenging due to the limited performance of existing …

Fast, in vivo voltage imaging using a red fluorescent indicator

M Kannan, G Vasan, C Huang, S Haziza, JZ Li… - Nature …, 2018 - nature.com
Genetically encoded voltage indicators (GEVIs) are emerging optical tools for acquiring
brain-wide cell-type-specific functional data at unparalleled temporal resolution. To broaden …

[HTML][HTML] Widefield imaging of rapid pan-cortical voltage dynamics with an indicator evolved for one-photon microscopy

X Lu, Y Wang, Z Liu, Y Gou, D Jaeger… - Nature …, 2023 - nature.com
Widefield imaging with genetically encoded voltage indicators (GEVIs) is a promising
approach for understanding the role of large cortical networks in the neural coding of …

[HTML][HTML] QuasAr Odyssey: the origin of fluorescence and its voltage sensitivity in microbial rhodopsins

A Silapetere, S Hwang, Y Hontani… - nature …, 2022 - nature.com
Rhodopsins had long been considered non-fluorescent until a peculiar voltage-sensitive
fluorescence was reported for archaerhodopsin-3 (Arch3) derivatives. These proteins …

A DNA-based voltmeter for organelles

A Saminathan, J Devany, AT Veetil, B Suresh… - Nature …, 2021 - nature.com
The role of membrane potential in most intracellular organelles remains unexplored
because of the lack of suitable tools. Here, we describe Voltair, a fluorescent DNA …