The fungal RABOME: RAB GTPases acting in the endocytic and exocytic pathways of Aspergillus nidulans (with excursions to other filamentous fungi)
M Pinar, MA Peñalva - Molecular Microbiology, 2021 - Wiley Online Library
RAB GTPases are major determinants of membrane identity that have been exploited as
highly specific reporters to study intracellular traffic in vivo. A score of fungal papers have …
highly specific reporters to study intracellular traffic in vivo. A score of fungal papers have …
The TRAPP complexes: oligomeric exchange factors that activate the small GTPases Rab1 and Rab11
The Transport Protein Particle (TRAPP) complexes are highly conserved multisubunit
complexes that act as nucleotide exchange factors (GEFs) for Rab GTPases. They act in …
complexes that act as nucleotide exchange factors (GEFs) for Rab GTPases. They act in …
Cryo‐EM structure of metazoan TRAPPIII, the multi‐subunit complex that activates the GTPase Rab1
A Galindo, VJ Planelles‐Herrero, G Degliesposti… - The EMBO …, 2021 - embopress.org
The TRAPP complexes are nucleotide exchange factors that play essential roles in
membrane traffic and autophagy. TRAPPII activates Rab11, and TRAPPIII activates Rab1 …
membrane traffic and autophagy. TRAPPII activates Rab11, and TRAPPIII activates Rab1 …
Structural basis for assembly of TRAPPII complex and specific activation of GTPase Ypt31/32
C Mi, L Zhang, G Huang, G Shao, F Yang, X You… - Science …, 2022 - science.org
Transport protein particle (TRAPP) complexes belong to the multiprotein tethering complex
and exist in three forms—core TRAPP/TRAPPI, TRAPPII, and TRAPPIII. TRAPPII activates …
and exist in three forms—core TRAPP/TRAPPI, TRAPPII, and TRAPPIII. TRAPPII activates …
Structure of a TRAPPII-Rab11 activation intermediate reveals GTPase substrate selection mechanisms
SR Bagde, JC Fromme - Science Advances, 2022 - science.org
Rab1 and Rab11 are essential regulators of the eukaryotic secretory and endocytic
recycling pathways. The transport protein particle (TRAPP) complexes activate these …
recycling pathways. The transport protein particle (TRAPP) complexes activate these …
The dissection of snares reveals key factors for vesicular trafficking to the endosome-like compartment and apicoplast via the secretory system in Toxoplasma gondii
S Cao, J Yang, J Fu, H Chen, H Jia - MBio, 2021 - Am Soc Microbiol
Vesicular trafficking is a fundamental cellular process involved in material transport in
eukaryotes, but the diversity of the intracellular compartments has prevented researchers …
eukaryotes, but the diversity of the intracellular compartments has prevented researchers …
The substrate specificity of the human TRAPPII complex's Rab-guanine nucleotide exchange factor activity
ML Jenkins, NJ Harris, U Dalwadi, KD Fleming… - Communications …, 2020 - nature.com
Abstract The TRAnsport Protein Particle (TRAPP) complexes act as Guanine nucleotide
exchange factors (GEFs) for Rab GTPases, which are master regulators of membrane …
exchange factors (GEFs) for Rab GTPases, which are master regulators of membrane …
The TRAPP complexes: discriminating GTPases in context
SR Bagde, JC Fromme - FEBS letters, 2023 - Wiley Online Library
Correct localization of Rab GTPases in cells is critical for proper function in membrane
trafficking. Guanine‐nucleotide exchange factors (GEFs) act as the primary determinants of …
trafficking. Guanine‐nucleotide exchange factors (GEFs) act as the primary determinants of …
The Uso1 globular head interacts with SNAREs to maintain viability even in the absence of the coiled-coil domain
Abstract Uso1/p115 and RAB1 tether ER-derived vesicles to the Golgi. Uso1/p115 contains
a globular-head-domain (GHD), a coiled-coil (CC) mediating dimerization/tethering, and a C …
a globular-head-domain (GHD), a coiled-coil (CC) mediating dimerization/tethering, and a C …
The type V myosin-containing complex HUM is a RAB11 effector powering movement of secretory vesicles
M Pinar, A Alonso, V de Los Ríos, I Bravo-Plaza… - IScience, 2022 - cell.com
In the apex-directed RAB11 exocytic pathway of Aspergillus nidulans, kinesin-1/KinA
conveys secretory vesicles (SVs) to the hyphal tip, where they are transferred to the type V …
conveys secretory vesicles (SVs) to the hyphal tip, where they are transferred to the type V …