Reconciling the distinct roles of angiogenic/anti-angiogenic factors in the placenta and maternal circulation of normal and pathological pregnancies
A Umapathy, LW Chamley, JL James - Angiogenesis, 2020 - Springer
A branched vascular network is crucial to placental development and is dependent on
factors such as vascular endothelial growth factor (VEGF), placental growth factor (PlGF) …
factors such as vascular endothelial growth factor (VEGF), placental growth factor (PlGF) …
[HTML][HTML] Role of nitric oxide in placental vascular development and function
BJ Krause, MA Hanson, P Casanello - Placenta, 2011 - Elsevier
Nitric oxide (NO) is one of the most pleiotropic signaling molecules at systemic and cellular
levels, participating in vascular tone regulation, cellular respiration, proliferation, apoptosis …
levels, participating in vascular tone regulation, cellular respiration, proliferation, apoptosis …
Intrauterine growth restriction—etiology and consequences: what do we know about the human situation and experimental animal models?
Embryonic and fetal growth depend on genetic and environmental factors, and the process
is the result of the interaction between these factors. About 7–9% of live-born infants have a …
is the result of the interaction between these factors. About 7–9% of live-born infants have a …
Angiogenesis in implantation
DS Torry, J Leavenworth, M Chang… - Journal of assisted …, 2007 - Springer
Problem Implantation failure and early pregnancy loss are common following natural
conceptions and they are particularly important clinical hurdles to overcome following …
conceptions and they are particularly important clinical hurdles to overcome following …
Endothelial eNOS/arginase imbalance contributes to vascular dysfunction in IUGR umbilical and placental vessels
BJ Krause, I Carrasco-Wong, A Caniuguir, J Carvajal… - Placenta, 2013 - Elsevier
Placental vascular tone is critically influenced by nitric oxide (NO) derived from endothelial
NO synthase (eNOS) activity. Placental vessels from pregnancies complicated with …
NO synthase (eNOS) activity. Placental vessels from pregnancies complicated with …
Endothelial dysfunction in pregnancy complications
J Kornacki, P Gutaj, A Kalantarova, R Sibiak… - Biomedicines, 2021 - mdpi.com
The endothelium, which constitutes the inner layer of blood vessels and lymphatic
structures, plays an important role in various physiological functions. Alterations in structure …
structures, plays an important role in various physiological functions. Alterations in structure …
Placental growth factor is a potent vasodilator of rat and human resistance arteries
G Osol, G Celia, N Gokina, C Barron… - American Journal …, 2008 - journals.physiology.org
The objectives of this study were to determine whether placental growth factor (PlGF) exerts
a vasodilatory effect on rat uterine vessels (arcuate arteries and veins) and to examine …
a vasodilatory effect on rat uterine vessels (arcuate arteries and veins) and to examine …
Placental treatment with insulin-like growth factor 1 via nanoparticle differentially impacts vascular remodeling factors in guinea pig sub-placenta/decidua
Clinically, fetal growth restriction (FGR) is only detectable in later gestation, despite
pathophysiological establishment likely earlier in pregnancy. Additionally, there are no …
pathophysiological establishment likely earlier in pregnancy. Additionally, there are no …
The gonadotropins: tissue-specific angiogenic factors?
K Reisinger, N Baal, T McKinnon, K Münstedt… - Molecular and cellular …, 2007 - Elsevier
The gonadotropins, whose members are human chorionic gonadotropin (hCG), lutenizing
hormone (LH) and follicle-stimulating hormone (FSH) are a well characterized hormone …
hormone (LH) and follicle-stimulating hormone (FSH) are a well characterized hormone …
Signaling regulation of fetoplacental angiogenesis
K Wang, J Zheng - The Journal of endocrinology, 2011 - pmc.ncbi.nlm.nih.gov
During normal pregnancy, dramatically increased placental blood flow is critical for fetal
growth and survival as well as neonatal birth weights and survivability. This increased blood …
growth and survival as well as neonatal birth weights and survivability. This increased blood …