Mycobacterium tuberculosis is a prototrophic, metabolically flexible bacterium that has
achieved a spread in the human population that is unmatched by any other bacterial …

The biology of mycobacteria is dominated by a complex cell envelope of unique composition
and structure and of exceptionally low permeability. This cell envelope is the basis of many …

The detection of tuberculosis currently relies upon insensitive and unspecific techniques;
newer diagnostics would ideally co-opt specific bacterial processes to provide real-time …

Mycobacterium tuberculosis (Mtb) is an exclusively human pathogen that proliferates within
phagosomes of host phagocytes. Host lipids are believed to provide the major carbon and …

The phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a carbohydrate
transport and phosphorylation system present in bacteria of all different phyla and in …

The amino acid-producing organism Corynebacterium glutamicum cannot utilize glycerol, a
stoichiometric by-product of biodiesel production. By heterologous expression of …

Covering: 1994 to June 2008 Actinomycetes produce mycothiol as their major low molecular
weight thiol, which parallels the functions of glutathione found in prokaryotes and most Gram …

The growth and nutritional requirements of mycobacteria have been intensively studied
since the discovery of Mycobacterium tuberculosis more than a century ago. However, the …

Mycobacterium tuberculosis, the causative agent of tuberculosis, is one of the most
important bacterial pathogens. Recent work has revealed that the natural bactericidal …

Soil dwelling Streptomyces species are faced with large variations in carbon or nitrogen
sources, phosphate, oxygen, iron, sulfur, and other nutrients. These drastic changes in key …