Background Physical frailty and sarcopenia show extensive clinical similarities. Whether
biomarkers exist that are shared by the two conditions is presently unclear. Methods We …

Frailty is an age-related clinical condition characterised by an increased susceptibility to
stressors and an elevated risk of adverse outcomes such as mortality. In the light of global …

Background Systemic chronic inflammation has been proposed as an essential mediating
factor in frailty, and several studies tested its relationship with frailty. However, the issue is …

Frailty is a common geriatric syndrome characterized by increased vulnerability and is
associated with adverse clinical events such as falls, hospitalization, and death. Early …

Introduction Ageing is associated with several physiological changes, including changes in
the immune system. Age-related changes in the innate and adaptive immune system are …

Chronic low-grade elevations of blood-borne cytokines/chemokines in older age tend to
associate with frailty in humans. This persistent inflammation is often called “inflammageing” …

Frailty is a major public issue that affects the physical health and quality of life of older
adults, especially as the population ages. Chronic low-grade inflammation has been …

Background Biological markers contribute to the precise intervention across the continuum
of frailty severity. Few studies have explored the advantages of biological markers collected …

衰弱已被视为一个重大的公共卫生问题, 相对于大规模筛查老年衰弱的量表类工具而言,
生物标志物可以更早, 更客观地识别衰弱高危人群. 本文对与衰弱相关的炎症, 内分泌 …

Background: One of the physiological changes that is most closely associated with frailty is
the increase in pro-inflammatory cytokines, and IL-6 in particular. Most studies have …