Peripheral markers of depression
A Nobis, D Zalewski, N Waszkiewicz - Journal of clinical medicine, 2020 - mdpi.com
Major Depressive Disorder (MDD) is a leading cause of disability worldwide, creating a high
medical and socioeconomic burden. There is a growing interest in the biological …
medical and socioeconomic burden. There is a growing interest in the biological …
Dissecting early life stress-induced adolescent depression through epigenomic approach
S Ochi, Y Dwivedi - Molecular psychiatry, 2023 - nature.com
Early life stress (ELS), such as abuse and neglect during childhood, can lead to psychiatric
disorders in later life. Previous studies have suggested that ELS can cause profound …
disorders in later life. Previous studies have suggested that ELS can cause profound …
A blood based 12-miRNA signature of Alzheimer disease patients
P Leidinger, C Backes, S Deutscher, K Schmitt… - Genome biology, 2013 - Springer
Background Alzheimer disease (AD) is the most common form of dementia but the
identification of reliable, early and non-invasive biomarkers remains a major challenge. We …
identification of reliable, early and non-invasive biomarkers remains a major challenge. We …
MicroRNA 135 is essential for chronic stress resiliency, antidepressant efficacy, and intact serotonergic activity
The link between dysregulated serotonergic activity and depression and anxiety disorders is
well established, yet the molecular mechanisms underlying these psychopathologies are not …
well established, yet the molecular mechanisms underlying these psychopathologies are not …
Epigenetic regulation in major depression and other stress-related disorders: molecular mechanisms, clinical relevance and therapeutic potential
M Yuan, B Yang, G Rothschild, JJ Mann… - Signal transduction and …, 2023 - nature.com
Major depressive disorder (MDD) is a chronic, generally episodic and debilitating disease
that affects an estimated 300 million people worldwide, but its pathogenesis is poorly …
that affects an estimated 300 million people worldwide, but its pathogenesis is poorly …
miR-1202 is a primate-specific and brain-enriched microRNA involved in major depression and antidepressant treatment
Major depressive disorder (MDD) is a prevalent mood disorder that is associated with
differential prefrontal brain expression patterns. Treatment of MDD includes a variety of …
differential prefrontal brain expression patterns. Treatment of MDD includes a variety of …
[HTML][HTML] Brain-derived neurotrophic factor and mental disorders
CC Lin, TL Huang - Biomedical Journal, 2020 - Elsevier
Brain-derived neurotrophic factor (BDNF) is a neurotrophin that modulates neuroplasticity in
the brain, and is one of the most widely investigated molecule in psychiatric disorders. The …
the brain, and is one of the most widely investigated molecule in psychiatric disorders. The …
Are the epigenetic changes predictive of therapeutic efficacy for psychiatric disorders? A translational approach towards novel drug targets
V Micale, M Di Bartolomeo, S Di Martino, T Stark… - Pharmacology & …, 2023 - Elsevier
The etiopathogenesis of mental disorders is not fully understood and accumulating evidence
support that clinical symptomatology cannot be assigned to a single gene mutation, but it …
support that clinical symptomatology cannot be assigned to a single gene mutation, but it …
Epigenetic regulations in neuropsychiatric disorders
Precise genetic and epigenetic spatiotemporal regulation of gene expression is critical for
proper brain development, function and circuitry formation in the mammalian central nervous …
proper brain development, function and circuitry formation in the mammalian central nervous …
MicroRNAs and exosomes in depression: potential diagnostic biomarkers
J Tavakolizadeh, K Roshanaei… - Journal of Cellular …, 2018 - Wiley Online Library
Depression is known as one of important psychiatric disorders which could be associated
with disability among various populations. Diagnostic and statistical manual of mental …
with disability among various populations. Diagnostic and statistical manual of mental …