Non-coding RNAs (ncRNAs) are a heterogeneous group of transcripts that, by definition, are
not translated into proteins. Since their discovery, ncRNAs have emerged as important …

Cells must adapt to changes in their environment to maintain cell, tissue and organismal
integrity in the face of mechanical, chemical or microbiological stress. Nuclear factor-κB (NF …

Sepsis presents as a severe infectious disease frequently documented in clinical settings.
Characterized by its systemic inflammatory response syndrome, sepsis has the potential to …

The NLRP3 inflammasome has an important function in inflammation by promoting the
processing of pro-IL-1β and pro-IL-18 to their mature bioactive forms, and by inducing cell …

Pathogenic bacteria cause various infections worldwide, especially in immunocompromised
and other susceptible individuals, and are also associated with high infant mortality rates in …

The onset and the termination of innate immune response must be tightly regulated to
maintain homeostasis and prevent excessive inflammation, which can be detrimental to the …

An inflammatory response is essential for combating invading pathogens. Several effector
components, as well as immune cell populations, are involved in mounting an immune …

Ulcerative colitis (UC) is a chronic non-specific inflammatory bowel disease, which usually
manifests as abdominal pain, diarrhea and hematochezia. The disease often recurs and is …

Radiation-induced lung injury (RILI) is a common complication in radiotherapy of thoracic
tumors and limits the therapeutic dose of radiation that can be given to effectively control …

MicroRNAs are a class of small noncoding RNAs that act as major post-transcriptional
regulators of gene expression. They are currently recognized for their important role in the …