[HTML][HTML] An updated review of lysophosphatidylcholine metabolism in human diseases
SH Law, ML Chan, GK Marathe, F Parveen… - International journal of …, 2019 - mdpi.com
Lysophosphatidylcholine (LPC) is increasingly recognized as a key marker/factor positively
associated with cardiovascular and neurodegenerative diseases. However, findings from …
associated with cardiovascular and neurodegenerative diseases. However, findings from …
The mechanisms of lysophosphatidylcholine in the development of diseases
Lysophosphatidylcholine (LPC) is the main component of oxidatively damaged low-density
lipoprotein (oxLDL). LPC originates from the cleavage of phosphatidylcholine by …
lipoprotein (oxLDL). LPC originates from the cleavage of phosphatidylcholine by …
How macrophages deal with death
G Lemke - Nature Reviews Immunology, 2019 - nature.com
Tissue macrophages rapidly recognize and engulf apoptotic cells. These events require the
display of so-called eat-me signals on the apoptotic cell surface, the most fundamental of …
display of so-called eat-me signals on the apoptotic cell surface, the most fundamental of …
[HTML][HTML] In vitro cell migration and invasion assays
CR Justus, N Leffler, M Ruiz-Echevarria… - Journal of visualized …, 2014 - ncbi.nlm.nih.gov
Migration is a key property of live cells and critical for normal development, immune
response, and disease processes such as cancer metastasis and inflammation. Methods to …
response, and disease processes such as cancer metastasis and inflammation. Methods to …
Gpr132 sensing of lactate mediates tumor–macrophage interplay to promote breast cancer metastasis
Macrophages are prominent immune cells in the tumor microenvironment that exert potent
effects on cancer metastasis. However, the signals and receivers for the tumor–macrophage …
effects on cancer metastasis. However, the signals and receivers for the tumor–macrophage …
[HTML][HTML] Lysophosphatidylcholine regulates sexual stage differentiation in the human malaria parasite Plasmodium falciparum
Transmission represents a population bottleneck in the Plasmodium life cycle and a key
intervention target of ongoing efforts to eradicate malaria. Sexual differentiation is essential …
intervention target of ongoing efforts to eradicate malaria. Sexual differentiation is essential …
Macrophage‐mediated tumor cell phagocytosis: opportunity for nanomedicine intervention
Macrophages are one of the most abundant non‐malignant cells in the tumor
microenvironment, playing critical roles in mediating tumor immunity. As important innate …
microenvironment, playing critical roles in mediating tumor immunity. As important innate …
[HTML][HTML] Acidic tumor microenvironment and pH-sensing G protein-coupled receptors
The tumor microenvironment is acidic due to glycolytic cancer cell metabolism, hypoxia, and
deficient blood perfusion. It is proposed that acidosis in the tumor microenvironment is an …
deficient blood perfusion. It is proposed that acidosis in the tumor microenvironment is an …
Mammalian G proteins and their cell type specific functions
N Wettschureck, S Offermanns - Physiological reviews, 2005 - journals.physiology.org
Heterotrimeric G proteins are key players in transmembrane signaling by coupling a huge
variety of receptors to channel proteins, enzymes, and other effector molecules. Multiple …
variety of receptors to channel proteins, enzymes, and other effector molecules. Multiple …
The sponge microbiome project
Rhododendron delavayi Franch. is globally famous as an ornamental plant. Its distribution in
southwest China covers several different habitats and environments. However, not much …
southwest China covers several different habitats and environments. However, not much …