Rebalancing of mitochondrial homeostasis through an NAD+-SIRT1 pathway preserves intestinal barrier function in severe malnutrition

C Ling, CJ Versloot, MEA Kvissberg, G Hu, N Swain… - …, 2023 - thelancet.com
Background The intestine of children with severe malnutrition (SM) shows structural and
functional changes that are linked to increased infection and mortality. SM dysregulates the …

Insights into the molecular mechanisms of malnutrition‐associated steatohepatitis: A review

V Sharma, V Patial - Liver International, 2024 - Wiley Online Library
Malnutrition is a public health epidemic mainly targeting poverty‐stricken people, young
ones, older people, pregnant women, and individuals with metabolic disorders. Severe …

DNA methylation of genes participating in hepatic metabolisms and function in fetal calf liver is altered by maternal undernutrition during gestation

S Muroya, K Otomaru, K Oshima, I Oshima… - International Journal of …, 2023 - mdpi.com
This study aimed to elucidate the effects of maternal undernutrition (MUN) on epigenetic
modification of hepatic genes in Japanese Black fetal calves during gestation. Using a …

Modified Linggui Zhugan Decoction protects against ventricular remodeling through ameliorating mitochondrial damage in post-myocardial infarction rats

M Xiang, X Zhao, Y Lu, Y Zhang, F Ding, L Lv… - Frontiers in …, 2023 - frontiersin.org
Introduction Modified Linggui Zhugan Decoction (MLZD) is a Traditional Chinese Medicine
prescription developed from Linggui Zhugan Decoction (LZD) that has been used for the …

[HTML][HTML] Hepatic mitochondrial and peroxisomal alterations in acutely ill malnourished Malawian children: a postmortem cohort study

CM Ling, TF Sheferaw, DM Denno, D Chasweka… - Global Pediatrics, 2024 - Elsevier
Objectives To describe and compare liver mitochondrial and peroxisomal histopathology by
nutritional status in children who died following hospitalization for acute illness in Malawi …

Mitochondrial Damage and Dysfunction in Severe Malnutrition

C Ling - 2023 - search.proquest.com
Background: Globally, undernutrition contributes to over 45% of deaths in children under five
years of age. Hospital mortality rates for children with severe malnutrition remain high …

[PDF][PDF] Mitochondrial Function in Severe Childhood Malnutrition

E Prokesh - 2024 - fse.studenttheses.ub.rug.nl
Severe malnutrition is a critical global health issue, affecting approximately 13.6 million
children and accounting for 20% of deaths in children under 5 worldwide. Despite …

The role of peroxisomes in malnutrition and metabolic disease: in vitro and in silico models

JH Nieto - 2024 - research.rug.nl
Diseases affecting normal fatty acid metabolism can be caused by either nutritional
dysregulations or genetic disorders. Traditionally, these disorders have been studied and …

[PDF][PDF] Docosahexaenoic acid prevents peroxisomal and mitochondrial protein loss in a murine hepatic organoid model of severe malnutrition

JM Horcas-Nieto, WA Rios-Ocampo… - research.rug.nl
Acute and chronic exposure to low amino acid conditions have been shown to lead to a
reduction in hepatic peroxisomal and mitochondrial content. There is limited understanding …

[PDF][PDF] PENGARUH MALNUTRISI PADA STRUKTUR DAN FUNGSI HATI: STUDI HISTOLOGI DAN KLINIS

A Roza, LSP Hewan - researchgate.net
Malnutrisi atau stunting masih menjadi masalah yang terus berlanjut. Menurut data dari
Bank Dunia dan UNICEF/WHO tahun 2018 menunjukkan bahwa sekitar 151 juta anak atau …