Genomic surveillance for antimicrobial resistance—a One Health perspective
Antimicrobial resistance (AMR)—the ability of microorganisms to adapt and survive under
diverse chemical selection pressures—is influenced by complex interactions between …
diverse chemical selection pressures—is influenced by complex interactions between …
Small-molecule antibiotic drug development: need and challenges
M Bergkessel, B Forte, IH Gilbert - ACS Infectious Diseases, 2023 - ACS Publications
The need for new antibiotics is urgent. Antimicrobial resistance is rising, although currently,
many more people die from drug-sensitive bacterial infections. The continued evolution of …
many more people die from drug-sensitive bacterial infections. The continued evolution of …
Bloodstream infections: mechanisms of pathogenesis and opportunities for intervention
CL Holmes, OR Albin, HLT Mobley… - Nature Reviews …, 2024 - nature.com
Bloodstream infections (BSIs) are common in hospitals, often life-threatening and increasing
in prevalence. Microorganisms in the blood are usually rapidly cleared by the immune …
in prevalence. Microorganisms in the blood are usually rapidly cleared by the immune …
Modulation of multidrug-resistant clone success in Escherichia coli populations: a longitudinal, multi-country, genomic and antibiotic usage cohort study
Background The effect of antibiotic usage on the success of multidrug-resistant (MDR)
clones in a population remains unclear. With this genomics-based molecular epidemiology …
clones in a population remains unclear. With this genomics-based molecular epidemiology …
Dominance of Escherichia coli sequence types ST73, ST95, ST127 and ST131 in Australian urine isolates: a genomic analysis of antimicrobial resistance and …
D Li, P Elankumaran, T Kudinha… - Microbial …, 2023 - microbiologyresearch.org
Extraintestinal pathogenic Escherichia coli (ExPEC) are the most frequent cause of urinary
tract infections (UTIs) globally. Most studies of clinical E. coli isolates are selected based on …
tract infections (UTIs) globally. Most studies of clinical E. coli isolates are selected based on …
Assessment of Prevalence and Diversity of Antimicrobial Resistant Escherichia coli from Retail Meats in Southern California
Retail meat products may serve as reservoirs and conduits for antimicrobial resistance,
which is frequently monitored using Escherichia coli as indicator bacteria. In this study, E …
which is frequently monitored using Escherichia coli as indicator bacteria. In this study, E …
[HTML][HTML] Genomic epidemiology of multidrug-resistant Escherichia coli and Klebsiella pneumoniae in Kenya, Uganda, and Jordan
DK Byarugaba, TS Osman… - Emerging Infectious …, 2024 - pmc.ncbi.nlm.nih.gov
Surveillance of antimicrobial resistance in Kenya, Uganda, and Jordan identified multidrug-
resistant high-risk bacterial clones: Escherichia coli sequence types 131, 1193, 69, 167, 10 …
resistant high-risk bacterial clones: Escherichia coli sequence types 131, 1193, 69, 167, 10 …
[HTML][HTML] Green synthesis, characterization and antimicrobial activity of iron oxide nanoparticles with tigecycline against multidrug resistant bacterial strains
MT Yassin, FO Al-Otibi, AA Al–Askar - Journal of King Saud University …, 2024 - Elsevier
Objectives The current study focused on the green synthesis of iron oxide nanoparticles
(IONPs) using Salvia officinalis leaf extract, aiming to control nosocomial infections caused …
(IONPs) using Salvia officinalis leaf extract, aiming to control nosocomial infections caused …
Pan-pathogen deep sequencing of nosocomial bacterial pathogens in Italy in spring 2020: a prospective cohort study
Background Nosocomial infections pose a considerable risk to patients who are susceptible,
and this is particularly acute in intensive care units when hospital-associated bacteria are …
and this is particularly acute in intensive care units when hospital-associated bacteria are …
Temporal dynamics of genetically heterogeneous extended-spectrum cephalosporin-resistant Escherichia coli bloodstream infections
WC Shropshire, B Strope, S Selvaraj Anand, J Bremer… - Msphere, 2023 - Am Soc Microbiol
Extended-spectrum cephalosporin-resistant Escherichia coli (ESC-R-Ec) is an urgent public
health threat with sequence type clonal complex 131 (STc131), phylogroup B2 strains being …
health threat with sequence type clonal complex 131 (STc131), phylogroup B2 strains being …