From leptin to other adipokines in health and disease: facts and expectations at the beginning of the 21st century

M Blüher, CS Mantzoros - Metabolism, 2015 - Elsevier
This year marks the 20th anniversary of the discovery of leptin, which has tremendously
stimulated translational obesity research. The discovery of leptin has led to realizations that …

Racial differences in cancer susceptibility and survival: more than the color of the skin?

BC Özdemir, GP Dotto - Trends in cancer, 2017 - cell.com
Epidemiological studies point to race as a determining factor in cancer susceptibility. In US
registries recording cancer incidence and survival by race (distinguishing 'black versus …

Adipose tissue and reproductive health

H Mathew, VD Castracane, C Mantzoros - Metabolism, 2018 - Elsevier
The understanding of adipose tissue role has evolved from that of a depot energy storage
organ to a dynamic endocrine organ. While genetics, sexual phenotype and sex steroids …

The molecular basis of breast cancer pathological phenotypes

YJ Heng, SC Lester, GMK Tse, RE Factor… - The Journal of …, 2017 - Wiley Online Library
The histopathological evaluation of morphological features in breast tumours provides
prognostic information to guide therapy. Adjunct molecular analyses provide further …

Obesity and breast cancer: molecular interconnections and potential clinical applications

V Simone, M D'avenia, A Argentiero, C Felici… - The …, 2016 - academic.oup.com
Obesity is an important risk factor for breast cancer (BC) in postmenopausal women;
interlinked molecular mechanisms might be involved in the pathogenesis. Increased levels …

Racial and socioeconomic disparities in presentation and outcomes of well-differentiated thyroid cancer

A Harari, N Li, MW Yeh - The Journal of Clinical Endocrinology & …, 2014 - academic.oup.com
Context: Racial/ethnic minorities suffer disproportionate morbidity and mortality from chronic
diseases. Objective: Our objective was to assess racial and socioeconomic status (SES) …

[HTML][HTML] Evolving role of adiponectin in cancer-controversies and update

A Katira, PH Tan - Cancer biology & medicine, 2016 - ncbi.nlm.nih.gov
Adiponectin (APN), an adipokine produced by adipocytes, has been shown to have a critical
role in the pathogenesis of obesity-associated malignancies. Through its receptor …

Genomic disparities in breast cancer among Latinas

F Lynce, KD Graves, L Jandorf, C Ricker… - Cancer …, 2016 - journals.sagepub.com
Background Breast cancer is the most common cancer diagnosed among Latinas in the
United States and the leading cause of cancer-related death among this population. Latinas …

Antipsychotic treatment in breast cancer patients

T Rahman, CV Clevenger… - American Journal of …, 2014 - Am Psychiatric Assoc
Special consideration is required when prescribing antipsychotic drugs for patients with an
existing diagnosis of breast cancer. The package inserts of all approved antipsychotics …

LEP rs7799039, LEPR rs1137101, and ADIPOQ rs2241766 and 1501299 polymorphisms are associated with obesity and chemotherapy response in Mexican women …

A Méndez-Hernández, MP Gallegos-Arreola… - Clinical breast …, 2017 - Elsevier
Background Obesity plays a major role in the pathogenesis of breast cancer. Leptin (LEP)
and adiponectin (ADIPOQ) are important in the regulation of adipose tissue. The response to …