Nitric oxide and the biology of pregnancy
S Zullino, F Buzzella, T Simoncini - Vascular Pharmacology, 2018 - Elsevier
Nitric oxide (NO) is a key regulator of both maternal and fetal homeostasis during
pregnancy, facilitating the maternal cardio-vascular changes, fetal development and growth …
pregnancy, facilitating the maternal cardio-vascular changes, fetal development and growth …
Physiological and Pathophysiological Role of Large-Conductance Calcium-Activated Potassium Channels (BKCa) in HUVECs and Placenta
F Neira, N Neira, J Torres, M González-Ortiz - Advances in Maternal-Fetal …, 2023 - Springer
BKCa channels (large-conductance Ca2+-activated K+ channels) play a critical role in
regulating vascular tone and blood pressure. These channels are present in the smooth …
regulating vascular tone and blood pressure. These channels are present in the smooth …
Reductions of circulating nitric oxide are followed by hypertension during pregnancy and increased activity of matrix metalloproteinases-2 and-9 in rats
RA Nascimento, JS Possomato-Vieira, GF Bonacio… - Cells, 2019 - mdpi.com
Hypertensive pregnancy has been associated with reduced nitric oxide (NO), bioavailability,
and increased activity of matrix metalloproteinases (MMPs). However, it is unclear if MMPs …
and increased activity of matrix metalloproteinases (MMPs). However, it is unclear if MMPs …
Decrease in nitric oxide production as a key mediator in the pathogenesis of preeclampsia and a potential therapeutic target: a case-control study
Pregnancy-induced hypertension (GH) complicates 6–10% of all pregnancies and, in 2019,
was responsible for approximately 28,000 deaths. The most common cause of gestational …
was responsible for approximately 28,000 deaths. The most common cause of gestational …
Serum from patients with hypertension promotes endothelial dysfunction to induce trophoblast invasion through the miR‑27b‑3p/ATPase plasma membrane Ca2+ …
L Zhu, Z Liu - Molecular Medicine Reports, 2021 - spandidos-publications.com
Pregnancy‑induced hypertension is often accompanied by preeclampsia. The present study
investigated whether microRNA (miR)‑27b‑3p affected the occurrence of preeclampsia by …
investigated whether microRNA (miR)‑27b‑3p affected the occurrence of preeclampsia by …
Hypertension, augmented activity of matrix metalloproteinases-2 and-9 and angiogenic imbalance in hypertensive pregnancy are attenuated by doxycycline
RA Nascimento, JS Possomato-Vieira… - European Journal of …, 2018 - Elsevier
Preeclampsia is manifested as maternal hypertension and fetal growth restriction. Matrix
metalloproteinases (MMPs) are involved in hypertension and doxycycline reduces blood …
metalloproteinases (MMPs) are involved in hypertension and doxycycline reduces blood …
Evidence of Nitric Oxide Impairment During Hypertensive Pregnancies
V Dela Justina, RR dos Passos Júnior, VV Lima… - Advances in Maternal …, 2023 - Springer
Hypertensive disorders of pregnancy complicate up to 10% of pregnancies worldwide, and
they can be classified into (1) gestational hypertension,(2) preeclampsia,(3) chronic …
they can be classified into (1) gestational hypertension,(2) preeclampsia,(3) chronic …
[PDF][PDF] Decrease in Nitric Oxide Production as a Key Mediator in the Pathogenesis of Preeclampsia and a Potential Therapeutic Target: A Case-Control Study …
Pregnancy-induced hypertension (GH) complicates 6–10% of all pregnancies and, in 2019,
was responsible for approximately 28,000 deaths. The most common cause of gestational …
was responsible for approximately 28,000 deaths. The most common cause of gestational …
Short-term outcomes of phosphodiesterase type 5 inhibitors for fetal growth restriction: a study protocol for a systematic review with individual participant data meta …
J Liauw, K Groom, W Ganzevoort, C Gluud… - Systematic …, 2021 - Springer
Background Early onset fetal growth restriction secondary to placental insufficiency can lead
to severe maternal and neonatal morbidity and mortality. Pre-clinical studies and a few small …
to severe maternal and neonatal morbidity and mortality. Pre-clinical studies and a few small …
[PDF][PDF] Andrew Sharp5, Laura Mackay2, Chirag Kariya6, Ken Lim1, Peter von Dadelszen7, Jacqueline Limpens3, Janus C. Jakobsen4, 8 and the STRIDER …
J Liauw, K Groom, W Ganzevoort, C Gluud… - 2021 - systematicreviewsjournal …
Background: Early onset fetal growth restriction secondary to placental insufficiency can
lead to severe maternal and neonatal morbidity and mortality. Pre-clinical studies and a few …
lead to severe maternal and neonatal morbidity and mortality. Pre-clinical studies and a few …