Dual-specificity, tyrosine phosphorylation-regulated kinases (DYRKs) and cdc2-like kinases (CLKs) in human disease, an overview
MF Lindberg, L Meijer - International Journal of Molecular Sciences, 2021 - mdpi.com
Dual-specificity tyrosine phosphorylation-regulated kinases (DYRK1A, 1B, 2-4) and cdc2-
like kinases (CLK1-4) belong to the CMGC group of serine/threonine kinases. These protein …
like kinases (CLK1-4) belong to the CMGC group of serine/threonine kinases. These protein …
The role of anillin/Mid1p during medial division and cytokinesis: from fission yeast to cancer cells
Cytokinesis is the final stage of cell division cycle when cellular constituents are separated
to produce two daughter cells. This process is driven by the formation and constriction of a …
to produce two daughter cells. This process is driven by the formation and constriction of a …
DYRK-family kinases regulate Candida albicans morphogenesis and virulence through the Ras1/PKA pathway
J MacAlpine, Z Liu, S Hossain, L Whitesell, N Robbins… - MBio, 2023 - Am Soc Microbiol
Candida albicans is an opportunistic human fungal pathogen that causes common
superficial mycoses in healthy populations and invasive disease in immunocompromised …
superficial mycoses in healthy populations and invasive disease in immunocompromised …
Multiple polarity kinases inhibit phase separation of F-BAR protein Cdc15 and antagonize cytokinetic ring assembly in fission yeast
Abstract The F-BAR protein Cdc15 is essential for cytokinesis in Schizosaccharomyces
pombe and plays a key role in attaching the cytokinetic ring (CR) to the plasma membrane …
pombe and plays a key role in attaching the cytokinetic ring (CR) to the plasma membrane …
Fission yeast Pak1 phosphorylates anillin-like Mid1 for spatial control of cytokinesis
JO Magliozzi, J Sears, L Cressey, M Brady… - Journal of Cell …, 2020 - rupress.org
Protein kinases direct polarized growth by regulating the cytoskeleton in time and space and
could play similar roles in cell division. We found that the Cdc42-activated polarity kinase …
could play similar roles in cell division. We found that the Cdc42-activated polarity kinase …
[HTML][HTML] Opposite surfaces of the Cdc15 F-BAR domain create a membrane platform that coordinates cytoskeletal and signaling components for cytokinesis
Many eukaryotes assemble an actin-and myosin-based cytokinetic ring (CR) on the plasma
membrane (PM) for cell division, but how it is anchored there remains unclear. In …
membrane (PM) for cell division, but how it is anchored there remains unclear. In …
Live-cell imaging defines a threshold in CDK activity at the G2/M transition
Cyclin-dependent kinase (CDK) determines the temporal ordering of the cell cycle phases.
However, despite significant progress in studying regulators of CDK and phosphorylation …
However, despite significant progress in studying regulators of CDK and phosphorylation …
Fission yeast paxillin contains two Cdc15 binding motifs for robust recruitment to the cytokinetic ring
CE Snider, R Bhattacharjee, MG Igarashi… - Molecular Biology of …, 2022 - Am Soc Cell Biol
The F-BAR protein Cdc15 mediates attachment of the cytokinetic ring (CR) to the plasma
membrane and is essential for cytokinesis in Schizosaccharomyces pombe. While its N …
membrane and is essential for cytokinesis in Schizosaccharomyces pombe. While its N …
Phosphorylation in the intrinsically disordered region of F-BAR protein Imp2 regulates its contractile ring recruitment
AH Willet, MG Igarashi, JS Chen… - Journal of cell …, 2021 - journals.biologists.com
ABSTRACT The F-BAR protein Imp2 is an important contributor to cytokinesis in the fission
yeast Schizosaccharomyces pombe. Because cell cycle-regulated phosphorylation of the …
yeast Schizosaccharomyces pombe. Because cell cycle-regulated phosphorylation of the …
Processes Controlling the Contractile Ring during Cytokinesis in Fission Yeast, Including the Role of ESCRT Proteins
IM Rezig, WG Yaduma, CJ McInerny - Journal of Fungi, 2024 - mdpi.com
Cytokinesis, as the last stage of the cell division cycle, is a tightly controlled process
amongst all eukaryotes, with defective division leading to severe cellular consequences and …
amongst all eukaryotes, with defective division leading to severe cellular consequences and …