Serotonin, food intake, and obesity

KA van Galen, KW Ter Horst, MJ Serlie - Obesity Reviews, 2021 - Wiley Online Library
The role of serotonin in food intake has been studied for decades. Food intake is mainly
regulated by two brain circuitries:(i) the homeostatic circuitry, which matches energy intake …

The role of central dopamine and serotonin in human obesity: lessons learned from molecular neuroimaging studies

KA van Galen, KW Ter Horst, J Booij, SE la Fleur… - Metabolism, 2018 - Elsevier
Obesity results from an imbalance between energy intake and expenditure, and many
studies have aimed to determine why obese individuals continue to (over) consume food …

Central noradrenaline transporter availability in highly obese, non-depressed individuals

S Hesse, GA Becker, M Rullmann, A Bresch… - European journal of …, 2017 - Springer
Purpose The brain noradrenaline (NA) system plays an important role in the central nervous
control of energy balance and is thus implicated in the pathogenesis of obesity. The specific …

The effect of obesity on the availabilities of dopamine and serotonin transporters

SB Nam, K Kim, BS Kim, HJ Im, SH Lee, SJ Kim… - Scientific reports, 2018 - nature.com
The authors investigated relations between obesity, age, and sex and the availabilities of
striatal dopamine transporter (DAT) and extrastriatal serotonin transporter (SERT) by 123I …

Overweight adults are more impulsive than normal weight adults: Evidence from ERPs during a chocolate-related delayed discounting task

Y Liu, J Zhao, X Zhang, X Gao, W Xu, H Chen - Neuropsychologia, 2019 - Elsevier
Overweight or obesity can be accompanied by abnormalities in executive function and
related neural markers. The aim of the present study was to investigate the behavioral and …

Effects of bariatric surgery and dietary interventions for obesity on brain neurotransmitter systems and metabolism: A systematic review of positron emission …

AS Al‐Alsheikh, S Alabdulkader, AD Miras… - Obesity …, 2023 - Wiley Online Library
This systematic review collates studies of dietary or bariatric surgery interventions for obesity
using positron emission tomography and single‐photon emission computed tomography. Of …

Neurocognitive correlates of food-related response inhibition in overweight/obese adults

Y Liu, X Gao, J Zhao, L Zhang, H Chen - Brain Topography, 2020 - Springer
Response inhibition is thought to play a critical role in the manifestation and maintenance of
obesity. The study aimed to investigate the behavioral and neural correlates of food-related …

Serotonin transporter binding in the diencephalon is reduced in insulin-resistant obese humans

RI Versteeg, KE Koopman, J Booij, MT Ackermans… - …, 2017 - karger.com
Background: Altered brain dopaminergic and serotonergic pathways have been shown in
obese rodents and humans, but it is unknown whether this is related to obesity per se or to …

Constitutionally high serotonin tone favors obesity: study on rat sublines with altered serotonin homeostasis

M Kesić, P Baković, M Horvatiček, BLJ Proust… - Frontiers in …, 2020 - frontiersin.org
Central and peripheral pools of biogenic monoamine serotonin (5-hydroxytryptamine [5HT])
exert opposite effects on the body weight regulation: increase in brain 5HT activity is …

Serotonin transporter gene promoter methylation status correlates with in vivo prefrontal 5-HTT availability and reward function in human obesity

M Drabe, M Rullmann, J Luthardt, Y Boettcher… - Translational …, 2017 - nature.com
A polymorphism in the promoter region of the human serotonin transporter (5-HTT)-coding
SLC6A4 gene (5-HTTLPR) has been implicated in moderating susceptibility to stress-related …