Aging is an important risk factor for several human diseases such as cancer, cardiovascular
disease and neurodegenerative disorders, resulting from a combination of genetic and …

While clinical gene therapy celebrates its first successes, with several products already
approved for clinical use and several hundreds in the final stages of the clinical approval …

Novel bio-therapeutic agents that harness the properties of small, non-coding nucleic acids
hold great promise for clinical applications. These include antisense oligonucleotides that …

Gene expression is needed for the maintenance of heart function under normal conditions
and in response to stress. Each cell type of the heart has a specific program controlling …

The sensitivity of myocardium is enhanced to ischemia/reperfusion (I/R) injury under PM2. 5
exposure. It is still under prelude for lncRNA-miRNA pair in the study of aggravated …

Osteosarcoma is an aggressive malignant neoplasm in teenagers and young adults. Long
non-coding RNA (lncRNA) taurine-upregulated gene 1 (TUG1) is considered as an …

Accumulating evidence has been obtained to understand the mechanisms of long non-
coding RNAs (lncRNAs) in bladder cancer (BC). However, due to the recurrence and …

A transcriptional program implemented by transcription factors and epigenetic regulators
governs cardiac development and disease. Mutations in these factors are important causes …

Abstracts Backgrounds Several studies have explored the prognostic value of long non-
coding RNA ZEB1 antisense RNA 1 (lncRNA ZEB1-AS1) in various types of cancer …

Cutaneous T-cell lymphomas (CTCLs) represent a large, heterogeneous group of non-
Hodgkin lymphomas that primarily affect the skin. Among multiple CTCL variants, the most …