As the mainstay in the treatment of various cancers, chemotherapy plays a vital role, but still
faces many challenges, such as poor tumour selectivity and multidrug resistance (MDR) …

Nanotechnology has been widely used in the development of new strategies for drug
delivery and cancer therapy. Compared to traditional drug delivery systems, nano-based …

The folate receptor is a highly selective tumor marker overexpressed in greater than 90% of
ovarian carcinomas. Two general strategies have been developed for the targeted delivery …

The receptor for folic acid constitutes a useful target for tumor-specific drug delivery,
primarily because:(1) it is upregulated in many human cancers, including malignancies of …

1.1. General Strategies in the Design of Tumor Targeted Therapeutics. Today's quest for
developing tumor-targeted therapies has naturally followed two nonoverlapping strategies …

The folate receptor (FR) is a confirmed tumor-associated antigen that binds folate and folate–
drug conjugates with very high affinity and shuttles these bound molecules inside cells via …

A biomolecular–inorganic hybrid is formed from anionic biomolecules (such as DNA
fragments, ATP, or an antisense oligonucleotide) intercalated in a cationic Mg/Al layered …

Antibody or ligand-mediated targeting of liposomal anticancer drugs to antigens expressed
selectively or over-expressed on tumor cells is increasingly being recognized as an effective …

Cancer is a killer disease second only to heart problems. 1 Though there is significant
progress in the field of anticancer technology, we are still badly in need of a reliable cure for …

Liposomes are being increasingly utilized to deliver drugs, enzymes, antisense
oligonucleotides, and genes to various therapeutic targets. Liposome-mediated delivery of …