[HTML][HTML] Neural regulations of the tumor microenvironment

AC Restaino, PD Vermeer - FASEB BioAdvances, 2022 - ncbi.nlm.nih.gov
The identification of nerves in the tumor microenvironment has ushered in a new area of
research in cancer biology. Numerous studies demonstrate the presence of various types of …

Circulating metabolite biomarkers: A game changer in the human prostate cancer diagnosis

S Krishnan, S Kanthaje, DR Punchappady… - Journal of Cancer …, 2023 - Springer
Abstract Purpose Prostate cancer (PCa) is the second most commonly diagnosed cancer in
men in Western and Asian countries. Serum prostate-specific antigen (PSA) test has been …

Target metabolome profiling-based machine learning as a diagnostic approach for cardiovascular diseases in adults

NE Moskaleva, KM Shestakova, AV Kukharenko… - Metabolites, 2022 - mdpi.com
Metabolomics is a promising technology for the application of translational medicine to
cardiovascular risk. Here, we applied a liquid chromatography/tandem mass spectrometry …

Pharmacological targets of SGLT2 inhibition on prostate cancer mediated by circulating metabolites: a drug-target Mendelian randomization study

Y Lin, Y Zhang, S Wang, L Cao, R Zhao, X Ma… - Frontiers in …, 2024 - frontiersin.org
Background The relationship between sodium-glucose cotransporter 2 (SGLT2) inhibitors
and prostate cancer is still unknown. Although these inhibitors can influence tumor …

Causality of genetically determined metabolites on susceptibility to prevalent urological cancers: a two-sample Mendelian randomization study and meta-analysis

X Dai, H Wang, R Zhong, J Li, Y Hou - Frontiers in Genetics, 2024 - frontiersin.org
Background Prevalent urological cancers, including kidney, prostate, bladder, and testicular
cancers, contribute significantly to global cancer incidence and mortality. Metabolomics …

A unique urinary metabolic feature for the determination of bladder cancer, prostate cancer, and renal cell carcinoma

S Lee, JY Ku, BJ Kang, KH Kim, HK Ha, S Kim - Metabolites, 2021 - mdpi.com
Prostate cancer (PCa), bladder cancer (BCa), and renal cell carcinoma (RCC) are the most
prevalent cancer among urological cancers. However, there are no cancer-specific …

[HTML][HTML] Prostate cancer-derived extracellular vesicles metabolic biomarkers: Emerging roles for diagnosis and prognosis

MA Hamed, V Wasinger, Q Wang, P Graham… - Journal of Controlled …, 2024 - Elsevier
Prostate cancer (PCa) is a global health concern, ranking as the most common cancer
among men in Western countries. Traditional diagnostic methods are invasive with adverse …

Targeted profiling of polar metabolites in cancer metabolic reprogramming by hydrophilic interaction liquid chromatography-tandem mass spectrometry

XM Dong, P Wu, LH Cheng, L Shou, H Dong… - … of Chromatography A, 2022 - Elsevier
Metabolic reprogramming of cancer cells is a hallmark of cancer, in which the polar
metabolites involving aerobic glycolysis, pentose phosphate pathway (PPP), tricarboxylic …

1H-NMR-based urine metabolomics of prostate cancer and benign prostatic hyperplasia

M Zniber, T Lamminen, P Taimen, PJ Boström… - Heliyon, 2024 - cell.com
Abstract Background Prostate cancer (PCa) and benign prostatic hyperplasia (BPH) are
prevalent conditions affecting a significant portion of the male population, particularly with …

Carcinogenic effect of adenylosuccinate lyase (ADSL) in prostate cancer development and progression through the cell cycle pathway

J Liao, Q Song, J Li, K Du, Y Chen, C Zou… - Cancer Cell International, 2021 - Springer
Abstract Background Prostate cancer (PCa) is still a serious male malignant disease across
the world. However, no exact pathogenesis had been explained. Although adenylosuccinate …