Chronic kidney disease (CKD) triggers the risk of developing uremic cardiomyopathy as
characterized by cardiac hypertrophy, fibrosis and functional impairment. Traditionally …

Background Elevated serum urea levels are common in moderate-to-advanced chronic
kidney disease (CKD). Several studies have shown that urea is a direct and indirect uraemic …

Background Blood urea nitrogen (BUN) reflects decreased glomerular filtration rate (GFR).
The effect of BUN on clinical outcomes, excluding the impact of GFR, in heart failure with …

Depression is common in patients with chronic kidney disease (CKD). Experimental studies
suggest the role of urea toxicity in depression. We assessed both the incidence of …

Uremic cardiomyopathy (UCM) is a common complication in patients with chronic kidney
disease (CKD) and an important risk factor for death. P-Cresyl sulfate (PCS) is a damaging …

Chronic kidney diseases (CKD) have genetic associations with kidney function. Univariate
genome-wide association studies (GWAS) have identified single nucleotide polymorphisms …

This study aimed to explore the regulatory role of lncRNA ANRIL/miR-181b-5p/S1PR1 in
UC. UC mouse model was established by 5/6th nephrectomy. We detected body weight …

Uraemic cardiomyopathy (UCM) is one of the most common complications in chronic kidney
disease (CKD). Our aim was to compare characteristics of various UCM mouse models …

Hyponatremia is the most common disorder of electrolyte imbalances. It is necessary to
develop new type of diuretics to treat hyponatremia without losing electrolytes. Urea …

This study aimed to investigate the relationship between blood urea nitrogen to albumin
ratio (BAR) and the prognosis of heart failure (HF). A total of 2125 patients with HF were …