Magnetic particle imaging: current applications in biomedical research
N Talebloo, M Gudi, N Robertson… - Journal of Magnetic …, 2020 - Wiley Online Library
Magnetic particle imaging (MPI) is a new imaging modality with the potential for high‐
resolution imaging while retaining the noninvasive nature of other current modalities such as …
resolution imaging while retaining the noninvasive nature of other current modalities such as …
[HTML][HTML] Magnetic particle imaging of islet transplantation in the liver and under the kidney capsule in mouse models
Background Islet transplantation (Tx) represents the most promising therapy to restore
normoglycemia in type 1 diabetes (T1D) patients to date. As significant islet loss has been …
normoglycemia in type 1 diabetes (T1D) patients to date. As significant islet loss has been …
[HTML][HTML] RNA aptamers specific for transmembrane p24 trafficking protein 6 and Clusterin for the targeted delivery of imaging reagents and RNA therapeutics to human …
D Van Simaeys, A De La Fuente, S Zilio, A Zoso… - Nature …, 2022 - nature.com
The ability to detect and target β cells in vivo can substantially refine how diabetes is studied
and treated. However, the lack of specific probes still hampers a precise characterization of …
and treated. However, the lack of specific probes still hampers a precise characterization of …
Artificial intelligence analysis of magnetic particle imaging for islet transplantation in a mouse model
Purpose Current approaches to quantification of magnetic particle imaging (MPI) for cell-
based therapy are thwarted by the lack of reliable, standardized methods of segmenting the …
based therapy are thwarted by the lack of reliable, standardized methods of segmenting the …
[HTML][HTML] Transplanted adipose-derived stem cells can be short-lived yet accelerate healing of acid-burn skin wounds: a multimodal imaging study
The incidence of accidental and intentional acid skin burns is rising. Current treatment
strategies are mostly inadequate, leaving victims disfigured and without treatment options …
strategies are mostly inadequate, leaving victims disfigured and without treatment options …
Phase-changing citrate macromolecule combats oxidative pancreatic islet damage, enables islet engraftment and function in the omentum
Clinical outcomes for total-pancreatectomy followed by intraportal islet autotransplantation
(TP-IAT) to treat chronic pancreatitis (CP) are suboptimal due to pancreas inflammation …
(TP-IAT) to treat chronic pancreatitis (CP) are suboptimal due to pancreas inflammation …
[HTML][HTML] Beta cell imaging—From pre-clinical validation to first in man testing
S Demine, ML Schulte, PR Territo… - International journal of …, 2020 - mdpi.com
There are presently no reliable ways to quantify human pancreatic beta cell mass (BCM) in
vivo, which prevents an accurate understanding of the progressive beta cell loss in diabetes …
vivo, which prevents an accurate understanding of the progressive beta cell loss in diabetes …
Monitoring β-cell survival after intrahepatic islet transplantation using dynamic exendin PET imaging: a proof-of-concept study in individuals with type 1 diabetes
TJP Jansen, M Buitinga, M Boss, MF Nijhoff, M Brom… - Diabetes, 2023 - Am Diabetes Assoc
Intrahepatic transplantation of islets of Langerhans (ITx) is a treatment option for individuals
with complicated type 1 diabetes and profoundly unstable glycemic control, but its …
with complicated type 1 diabetes and profoundly unstable glycemic control, but its …
Protection of pancreatic islets using theranostic silencing nanoparticles in a baboon model of islet transplantation
The long-term success of pancreatic islet transplantation (Tx) as a cure for type 1 diabetes
remains limited. Islet loss after Tx related to apoptosis, inflammation, and other factors …
remains limited. Islet loss after Tx related to apoptosis, inflammation, and other factors …
[HTML][HTML] Islet transplantation
L Piemonti - 2015 - europepmc.org
Transplanting islets of Langerhans consists of implantation in the recipient's hepatic portal
system of endocrine pancreatic tissue, with a variable degree of purification. The field of islet …
system of endocrine pancreatic tissue, with a variable degree of purification. The field of islet …