Insights into the sperm chromatin and implications for male infertility from a protein perspective
Male germ cells undergo an extreme but fascinating process of chromatin remodeling that
begins in the testis during the last phase of spermatogenesis and continues through …
begins in the testis during the last phase of spermatogenesis and continues through …
[HTML][HTML] Proteomic analysis of histone variants and their PTMs: strategies and pitfalls
Epigenetic modifications contribute to the determination of cell fate and differentiation. The
molecular mechanisms underlying histone variants and post-translational modifications …
molecular mechanisms underlying histone variants and post-translational modifications …
[HTML][HTML] Spermatid-specific linker histone HILS1 is a poor condenser of DNA and chromatin and preferentially associates with LINE-1 elements
Background Linker histones establish and maintain higher-order chromatin structure. Eleven
linker histone subtypes have been reported in mammals. HILS1 is a spermatid-specific …
linker histone subtypes have been reported in mammals. HILS1 is a spermatid-specific …
[HTML][HTML] Linker histone variant H1t is closely associated with repressed repeat-element chromatin domains in pachytene spermatocytes
IA Mahadevan, S Kumar, MRS Rao - Epigenetics & Chromatin, 2020 - Springer
Background H1t is the major linker histone variant in pachytene spermatocytes, where it
constitutes 50–60% of total H1. This linker histone variant was previously reported to …
constitutes 50–60% of total H1. This linker histone variant was previously reported to …
[HTML][HTML] Identification and analysis of Six phosphorylation sites within the xenopus laevis linker histone H1. 0 C-Terminal domain indicate distinct effects on …
As a key structural component of the chromatin of higher eukaryotes, linker histones (H1s)
are involved in stabilizing the folding of extended nucleosome arrays into higher-order …
are involved in stabilizing the folding of extended nucleosome arrays into higher-order …