[HTML][HTML] Allergen immunotherapy: past, present and future

SR Durham, MH Shamji - Nature Reviews Immunology, 2023 - nature.com
Allergen immunotherapy is a form of therapeutic vaccination for established IgE-mediated
hypersensitivity to common allergen sources such as pollens, house dust mites and the …

The role of allergen‐specific IgE, IgG and IgA in allergic disease

MH Shamji, R Valenta, T Jardetzky, V Verhasselt… - Allergy, 2021 - Wiley Online Library
Immunoglobulin E (IgE)‐mediated allergy is the most common hypersensitivity disease
affecting more than 30% of the population. Exposure to even minute quantities of allergens …

Nomenclature of allergic diseases and hypersensitivity reactions: Adapted to modern needs: An EAACI position paper

M Jutel, I Agache, M Zemelka‐Wiacek, M Akdis… - Allergy, 2023 - Wiley Online Library
The exponential growth of precision diagnostic tools, including omic technologies, molecular
diagnostics, sophisticated genetic and epigenetic editing, imaging and nano‐technologies …

[HTML][HTML] Mechanisms of allergen immunotherapy for inhaled allergens and predictive biomarkers

MH Shamji, SR Durham - Journal of Allergy and Clinical Immunology, 2017 - Elsevier
Allergen immunotherapy is effective in patients with IgE-dependent allergic rhinitis and
asthma. When immunotherapy is given continuously for 3 years, there is persistent clinical …

Biomarkers for monitoring clinical efficacy of allergen immunotherapy for allergic rhinoconjunctivitis and allergic asthma: an EAACI Position Paper

MH Shamji, JH Kappen, M Akdis, E Jensen‐Jarolim… - Allergy, 2017 - Wiley Online Library
Background Allergen immunotherapy (AIT) is an effective treatment for allergic
rhinoconjunctivitis (AR) with or without asthma. It is important to note that due to the complex …

[HTML][HTML] Guideline on allergen immunotherapy in IgE-mediated allergic diseases: S2K guideline of the German society of allergology and clinical immunology (DGAKI) …

O Pfaar, T Ankermann, M Augustin, P Bubel… - Allergologie …, 2022 - ncbi.nlm.nih.gov
Pneumologists, Sleep and Respiratory Physicians (BdP)(Sebastian Böing), Professional
Association of German Dermatologists (BVDD)(Klaus Strömer) were taking part in the …

Secretory IgA's complex roles in immunity and mucosal homeostasis in the gut

NJ Mantis, N Rol, B Corthésy - Mucosal immunology, 2011 - nature.com
Abstract Secretory IgA (SIgA) serves as the first line of defense in protecting the intestinal
epithelium from enteric toxins and pathogenic microorganisms. Through a process known as …

Multi-faceted functions of secretory IgA at mucosal surfaces

B Corthésy - Frontiers in immunology, 2013 - frontiersin.org
Secretory IgA (SIgA) plays an important role in the protection and homeostatic regulation of
intestinal, respiratory, and urogenital mucosal epithelia separating the outside environment …

Allergen immunotherapy: a practice parameter third update

L Cox, H Nelson, R Lockey, C Calabria… - Journal of Allergy and …, 2011 - jacionline.org
This document builds on the previous Joint Task Force document ''Allergen immunotherapy:
a practice parameter second update''published in the Journal of Allergy and Clinical …

Toll-like receptor agonists as adjuvants for allergen immunotherapy

ME Kirtland, DC Tsitoura, SR Durham… - Frontiers in …, 2020 - frontiersin.org
Toll-like receptors (TLRs) are essential components of innate immunity and provide
defensive inflammatory responses to invading pathogens. Located within the plasma …