Radiation therapy (RT) plays a key role in curative-intent treatments for head and neck
cancers. Its use is indicated as a sole therapy in early stage tumors or in combination with …

Background In the management of head and neck cancer (HNC) patients, local recurrence
is a common cause of treatment failure. Only a few patients with recurrent HNC (rHNC) are …

Purpose Salvage options for unresectable locally recurrent, previously irradiated squamous
cell carcinoma of the head and neck (rSCCHN) are limited. Although the addition of …

Simple Summary The purpose of this manuscript is to illustrate the difficulties associated
with the treatment of the patient with recurrent metastatic SCCHN. This type of patient is very …

Retreatment of recurrent or second primary head and neck cancers occurring in a previously
irradiated field is complex. Few guidelines exist to support practice. We performed an …

Background and purpose Head and neck squamous cell carcinoma (HNSCC) that recurs
locally is a therapeutic challenge. We investigated the efficacy of boron neutron capture …

Simple Summary Head and neck cancers are highly prevalent worldwide. Despite the recent
advances in cancer diagnosis and treatment, more than 50% of the cases relapse within 2 …

Purpose To evaluate the potential benefit of 4π radiation therapy in recurrent, locally
advanced, or metastatic head-and-neck cancer treated with stereotactic body radiation …

Head and neck cancer is a kind of cancer which can be eradicated from radical radiation
therapy. However, with best efforts, nearly 40% patients will experience locoregional …

Cancer affects 39.6% of Americans at some point during their lifetime. Solid tumor
microenvironments are characterized by a disorganized, leaky vasculature that promotes …