Epidemiological evidence links an individual's susceptibility to chronic disease in adult life to
events during their intrauterine phase of development. Biologically this should not be …

The utero-placental circulation links the maternal and fetal circulations during pregnancy,
ensuring adequate gas and nutrient exchange, and consequently fetal growth. However, our …

Although a full understanding of the hepatic circulation is one of the keys to successfully
perform liver surgery and to elucidate liver pathology, relatively little is known about the …

Hypothermic machine perfusion (HMP) is experiencing a revival in organ preservation due
to the limitations of static cold storage and the need for better preservation of expanded …

Introduction Placental functional impairment in pregnancies with fetal growth restriction
(FGR) can arise from fetoplacental vascular abnormalities. We aimed to compare the micro …

Fetal growth restriction (FGR) affects 5–10% of pregnancies, leading to clinically significant
fetal morbidity and mortality. FGR placentae frequently exhibit poor vascular branching, but …

The placenta provides all the nutrients required for the fetus through pregnancy. It develops
dynamically, and, to avoid rejection of the fetus, there is no mixing of fetal and maternal …

Background The development of a biological based small diameter vascular graft (d< 6 mm),
that can be properly stored over a long time period at− 196° C, in order to directly be used to …

Small diameter vascular grafts from human placenta, decellularized with either Triton X-100
(Triton) or SDS and crosslinked with heparin were constructed and characterized. Graft …

Fetal growth restriction (FGR) is a leading cause of perinatal morbidity and mortality. Altered
placental formation and functional capacity are major contributors to FGR pathogenesis …