Despite two decades of intensified research to understand and cure tuberculosis disease,
biological uncertainties remain and hamper progress. However, owing to collaborative …

Drug-resistant tuberculosis (TB) is estimated to cause 13% of all antimicrobial resistance-
attributable deaths worldwide and is driven by both ongoing resistance acquisition and …

Background We aimed to evaluate the effectiveness of contact investigation in comparison
with passive case detection alone, and estimate the yield of co-prevalent and incident …

Background Estimates suggest that at least 30 000 children develop multidrug-resistant or
rifampicin-resistant tuberculosis each year. Despite household contact management (HCM) …

Latent tuberculosis infection (LTBI) represents a subclinical, asymptomatic mycobacterial
state affecting approximately 25% of the global population. The substantial prevalence of …

Background An estimated one fourth of the world's population is infected with
Mycobacterium tuberculosis, and 5–10% of those infected develop tuberculosis in their …

Children affected by rifampicin-resistant tuberculosis (RR-TB; TB resistant to at least
rifampicin) are a neglected group. Each year an estimated 25,000–30,000 children develop …

Preventing the progression of a drug-resistant tuberculosis (DR-TB) infection to disease is
an important pillar of the DR-TB elimination strategy. International guidelines have recently …

El presente estudio tuvo como objetivo realizar una validación de un aplicativo móvil Open
Data Kit (AM-ODK) en contactos expuestos a tuberculosis multidrogorresistente (TB-MDR) …

As Canada moves toward the elimination of tuberculosis (TB), the treatment of latent
tuberculosis infection (LTBI), referred to as tuberculosis preventive treatment (TPT), is …