The past two decades have seen a worldwide resurgence in infections caused by
Treponema pallidum subsp. pallidum, the syphilis spirochete. The well-recognized capacity …

Sexually transmitted diseases (STDs) are caused by several pathogens, including bacteria,
viruses and protozoa, and can induce male infertility through multiple pathophysiological …

Syphilis is a fascinating and perplexing infection, with protean clinical manifestations and
both diagnostic and management ambiguities. Treponema pallidum subsp. pallidum, the …

The agents of human treponematoses include four closely related members of the genus
Treponema: three subspecies of Treponema pallidum plus Treponema carateum. T …

Background The clinical syndrome associated with secondary syphilis (SS) reflects the
propensity of Treponema pallidum (Tp) to escape immune recognition while simultaneously …

Insights into the genomic adaptive traits of Treponema pallidum, the causative bacterium of
syphilis, have long been hampered due to the absence of in vitro culture models and the …

Comprehensive proteome-wide analysis of the syphilis spirochete, Treponema pallidum
ssp. pallidum, is technically challenging due to high sample complexity, difficulties with …

Background The yaws treponemes, Treponema pallidum ssp. pertenue (TPE) strains, are
closely related to syphilis causing strains of Treponema pallidum ssp. pallidum (TPA). Both …

Syphilis is a multistage disease caused by the invasive spirochete Treponema pallidum
subsp. pallidum. Despite inexpensive and effective antibiotic therapy, syphilis remains a …

Pathogenic uncultivable treponemes, similar to syphilis-causing Treponema pallidum
subspecies pallidum, include T. pallidum ssp. pertenue, T. pallidum ssp. endemicum and …