Treponema pallidum, the syphilis spirochete: making a living as a stealth pathogen
JD Radolf, RK Deka, A Anand, D Šmajs… - Nature Reviews …, 2016 - nature.com
The past two decades have seen a worldwide resurgence in infections caused by
Treponema pallidum subsp. pallidum, the syphilis spirochete. The well-recognized capacity …
Treponema pallidum subsp. pallidum, the syphilis spirochete. The well-recognized capacity …
Male infertility: a public health issue caused by sexually transmitted pathogens
F Gimenes, RP Souza, JC Bento, JJV Teixeira… - Nature Reviews …, 2014 - nature.com
Sexually transmitted diseases (STDs) are caused by several pathogens, including bacteria,
viruses and protozoa, and can induce male infertility through multiple pathophysiological …
viruses and protozoa, and can induce male infertility through multiple pathophysiological …
[HTML][HTML] Syphilis: using modern approaches to understand an old disease
EL Ho, SA Lukehart - The Journal of clinical investigation, 2011 - Am Soc Clin Investig
Syphilis is a fascinating and perplexing infection, with protean clinical manifestations and
both diagnostic and management ambiguities. Treponema pallidum subsp. pallidum, the …
both diagnostic and management ambiguities. Treponema pallidum subsp. pallidum, the …
The endemic treponematoses
L Giacani, SA Lukehart - Clinical microbiology reviews, 2014 - Am Soc Microbiol
The agents of human treponematoses include four closely related members of the genus
Treponema: three subspecies of Treponema pallidum plus Treponema carateum. T …
Treponema: three subspecies of Treponema pallidum plus Treponema carateum. T …
[HTML][HTML] Immune evasion and recognition of the syphilis spirochete in blood and skin of secondary syphilis patients: two immunologically distinct compartments
AR Cruz, LG Ramirez, AV Zuluaga… - PLoS neglected …, 2012 - journals.plos.org
Background The clinical syndrome associated with secondary syphilis (SS) reflects the
propensity of Treponema pallidum (Tp) to escape immune recognition while simultaneously …
propensity of Treponema pallidum (Tp) to escape immune recognition while simultaneously …
[HTML][HTML] Genome-scale analysis of the non-cultivable Treponema pallidum reveals extensive within-patient genetic variation
Insights into the genomic adaptive traits of Treponema pallidum, the causative bacterium of
syphilis, have long been hampered due to the absence of in vitro culture models and the …
syphilis, have long been hampered due to the absence of in vitro culture models and the …
[HTML][HTML] Deep proteome coverage advances knowledge of Treponema pallidum protein expression profiles during infection
Comprehensive proteome-wide analysis of the syphilis spirochete, Treponema pallidum
ssp. pallidum, is technically challenging due to high sample complexity, difficulties with …
ssp. pallidum, is technically challenging due to high sample complexity, difficulties with …
[HTML][HTML] Whole Genome Sequences of Three Treponema pallidum ssp. pertenue Strains: Yaws and Syphilis Treponemes Differ in Less than 0.2% of the Genome …
D Čejková, M Zobanikova, L Chen… - PLoS neglected …, 2012 - journals.plos.org
Background The yaws treponemes, Treponema pallidum ssp. pertenue (TPE) strains, are
closely related to syphilis causing strains of Treponema pallidum ssp. pallidum (TPA). Both …
closely related to syphilis causing strains of Treponema pallidum ssp. pallidum (TPA). Both …
Current status of syphilis vaccine development: need, challenges, prospects
CE Cameron, SA Lukehart - Vaccine, 2014 - Elsevier
Syphilis is a multistage disease caused by the invasive spirochete Treponema pallidum
subsp. pallidum. Despite inexpensive and effective antibiotic therapy, syphilis remains a …
subsp. pallidum. Despite inexpensive and effective antibiotic therapy, syphilis remains a …
[HTML][HTML] Genetic diversity in Treponema pallidum: implications for pathogenesis, evolution and molecular diagnostics of syphilis and yaws
D Šmajs, SJ Norris, GM Weinstock - Infection, Genetics and Evolution, 2012 - Elsevier
Pathogenic uncultivable treponemes, similar to syphilis-causing Treponema pallidum
subspecies pallidum, include T. pallidum ssp. pertenue, T. pallidum ssp. endemicum and …
subspecies pallidum, include T. pallidum ssp. pertenue, T. pallidum ssp. endemicum and …