Importance of the pig as a human biomedical model
JK Lunney, A Van Goor, KE Walker… - Science translational …, 2021 - science.org
Pigs have substantial potential as biomedical models for studying human developmental
processes, congenital diseases, and pathogen response mechanisms in addition to utility as …
processes, congenital diseases, and pathogen response mechanisms in addition to utility as …
Applications of CRISPR technologies in research and beyond
R Barrangou, JA Doudna - Nature biotechnology, 2016 - nature.com
Programmable DNA cleavage using CRISPR–Cas9 enables efficient, site-specific genome
engineering in single cells and whole organisms. In the research arena, versatile CRISPR …
engineering in single cells and whole organisms. In the research arena, versatile CRISPR …
Application of gene editing for climate change in agriculture
NG Karavolias, W Horner, MN Abugu… - Frontiers in Sustainable …, 2021 - frontiersin.org
Climate change imposes a severe threat to agricultural systems, food security, and human
nutrition. Meanwhile, efforts in crop and livestock gene editing have been undertaken to …
nutrition. Meanwhile, efforts in crop and livestock gene editing have been undertaken to …
Porcine reproductive and respiratory syndrome viruses (porcine arteriviruses)
JJ Zimmerman, SA Dee, DJ Holtkamp… - Diseases of …, 2019 - Wiley Online Library
Control of porcine reproductive and respiratory syndrome virus (PRRSV) remains
problematic, and economic studies have uniformly shown that PRRSV inflicts major losses …
problematic, and economic studies have uniformly shown that PRRSV inflicts major losses …
Precision engineering for PRRSV resistance in pigs: Macrophages from genome edited pigs lacking CD163 SRCR5 domain are fully resistant to both PRRSV …
C Burkard, SG Lillico, E Reid, B Jackson… - PLoS …, 2017 - journals.plos.org
Porcine Reproductive and Respiratory Syndrome (PRRS) is a panzootic infectious disease
of pigs, causing major economic losses to the world-wide pig industry. PRRS manifests …
of pigs, causing major economic losses to the world-wide pig industry. PRRS manifests …
CD163 and pAPN double-knockout pigs are resistant to PRRSV and TGEV and exhibit decreased susceptibility to PDCoV while maintaining normal production …
K Xu, Y Zhou, Y Mu, Z Liu, S Hou, Y Xiong, L Fang… - Elife, 2020 - elifesciences.org
Porcine reproductive and respiratory syndrome virus (PRRSV) and transmissible
gastroenteritis virus (TGEV) are two highly infectious and lethal viruses causing major …
gastroenteritis virus (TGEV) are two highly infectious and lethal viruses causing major …
Coinfections and their molecular consequences in the porcine respiratory tract
G Saade, C Deblanc, J Bougon, C Marois-Créhan… - Veterinary …, 2020 - Springer
Understudied, coinfections are more frequent in pig farms than single infections. In pigs, the
term “Porcine Respiratory Disease Complex”(PRDC) is often used to describe coinfections …
term “Porcine Respiratory Disease Complex”(PRDC) is often used to describe coinfections …
EMA and EFSA Joint Scientific Opinion on measures to reduce the need to use antimicrobial agents in animal husbandry in the European Union, and the resulting …
EMA Committee for Medicinal Products for … - EFSA …, 2017 - Wiley Online Library
EFSA and EMA have jointly reviewed measures taken in the EU to reduce the need for and
use of antimicrobials in food‐producing animals, and the resultant impacts on antimicrobial …
use of antimicrobials in food‐producing animals, and the resultant impacts on antimicrobial …
Potential of genome editing to improve aquaculture breeding and production
Aquaculture is the fastest growing food production sector and is rapidly becoming the
primary source of seafood for human diets. Selective breeding programs are enabling …
primary source of seafood for human diets. Selective breeding programs are enabling …
Application of preserved boar semen for artificial insemination: Past, present and future challenges
D Waberski, A Riesenbeck, M Schulze, KF Weitze… - Theriogenology, 2019 - Elsevier
Artificial insemination (AI) is now used for breeding more than 90% of the sows in most of the
world's primary pork producing countries. Despite the advancement of methods to …
world's primary pork producing countries. Despite the advancement of methods to …