The Absence of Retroelement Activity Is Characteristic for Childhood Acute Leukemias and Adult Acute Lymphoblastic Leukemia
S Urazbakhtin, A Smirnova, A Volakhava… - International Journal of …, 2022 - mdpi.com
Retroelements (RE) have been proposed as important players in cancerogenesis. Different
cancer types are characterized by a different level of tumor-specific RE insertions. In …
cancer types are characterized by a different level of tumor-specific RE insertions. In …
Mobile retroelements induced by hypomethylating agents are restricted to transpose in myeloid malignancies
Š Pavlová, M Krzyžánková, A Volakhava, A Smirnova… - bioRxiv, 2023 - biorxiv.org
Retroelements (RE) present in the human genome are silenced via multiple mechanisms,
including DNA methylation, to prevent their potentially mutagenic effect. RE activity …
including DNA methylation, to prevent their potentially mutagenic effect. RE activity …