Background The role of the human microbiome in health and disease is an emerging and
important area of research; however, there is a concern that African populations are under …

The human nasal passages host major human pathogens. Recent research suggests that
the microbial communities inhabiting the epithelial surfaces of the nasal passages are a key …

Background Chronic obstructive pulmonary disease (COPD) is a heterogeneous disease
characterized by frequent exacerbation phenotypes independent of disease stage …

Chlamydiae are highly successful strictly intracellular bacteria associated with diverse
eukaryotic hosts. Here we analyzed metagenome-assembled genomes of the “Genomes …

Streptococcus pneumoniae is the main bacterial pathogen involved in pneumonia.
Pneumococcal acquisition and colonization density is probably affected by viral co …

Multiple epidemiological studies identify Dolosigranulum pigrum as a candidate beneficial
bacterium based on its positive association with health, including negative associations with …

Highlights•Commensal regulation of the nasal mucosa restricts pathogen acquisition.•
Nonpathogenic Streptococcus species show promise as probiotics in humans.•Microbiome …

Background Children are less susceptible to SARS-CoV-2 infection and typically have
milder illness courses than adults, but the factors underlying these age-associated …

The stability and composition of the airway microbiome is an important determinant of
respiratory health. Some airway bacteria are considered to be beneficial due to their …

Background Emerging evidence shows that airway microbiota may modulate local immune
responses, thereby contributing to the susceptibility and severity of acute respiratory …