Using NMR to identify and characterize natural products

RC Breton, WF Reynolds - Natural product reports, 2013 - pubs.rsc.org
Covering: up to November 2012 Over the past 28 years there have been several thousand
publications describing the use of 2D NMR to identify and characterize natural products …

Ethnopharmacology and future drug development: the North American experience

NR Farnsworth - Journal of ethnopharmacology, 1993 - Elsevier
The major programs in North America designed to study plants as sources of potential drugs
in which ethnomedical information is used to some extent are reviewed. Most of this work is …

Choosing the best pulse sequences, acquisition parameters, postacquisition processing strategies, and probes for natural product structure elucidation by NMR …

WF Reynolds, RG Enríquez - Journal of natural products, 2002 - ACS Publications
The relative merits of different pairs of two-dimensional NMR pulse sequences (COSY-90 vs
COSY-45, NOESY vs T-ROESY, HSQC vs HMQC, HMBC vs CIGAR, etc.) are compared and …

Computer-assisted structure verification and elucidation tools in NMR-based structure elucidation

ME Elyashberg, AJ Williams, GE Martin - Progress in Nuclear Magnetic …, 2008 - Elsevier
Laboratories around the world are challenged by the task of either verifying chemical
structures or elucidating the chemical structures of unknowns; each structure verified or …

Structural elucidation with NMR spectroscopy: practical strategies for organic chemists

EE Kwan, SG Huang - European journal of organic chemistry, 2008 - Wiley Online Library
Practical strategies for the structural elucidation of small organic molecules are described for
typical organic chemists. The analysis of an unknown is divided into three stages. First …

Biological activities of Annona glabra

V Padmaja, V Thankamany, N Hara, Y Fujimoto… - Journal of …, 1995 - Elsevier
On a preliminary screening, substantial antimicrobial, antifungal and moderate insecticidal,
sporicidal and cytotoxic activities were observed for the hexane extract of the stem bark of …

Biologically active diterpenes from Aspilia mossambicensis, a chimpanzee medicinal plant

JE Page, F Balza, T Nishida, GHN Towers - Phytochemistry, 1992 - Elsevier
Two potent stimulators of uterine contraction, the diterpenes kaurenoic and grandiflorenic
acids, were isolated from leaves of Aspilia mossambicensis. Their presence supports a …

Minimizing the risk of deducing wrong natural product structures from NMR data

DC Burns, WF Reynolds - Magnetic Resonance in Chemistry, 2021 - Wiley Online Library
There continues to be a disturbing number of natural products reported in the literature
whose structures are incorrect. At least in part, this reflects the fact that many natural product …

Long‐range two‐dimensional heteronuclear chemical shift correlation

GE Martin, AS Zektzer - Magnetic resonance in chemistry, 1988 - Wiley Online Library
Long‐range heteronuclear chemical shift correlation has undergone a period of burgeoning
growth during the past 4 years. Initially, such correlations were made by simply reoptimizing …

Improved 13C1H shift correlation spectra for indirectly bonded carbons and hydrogens: The FLOCK sequence

WF Reynolds, S McLean… - Magnetic resonance …, 1989 - Wiley Online Library
Several modifications of the basic 13C 1H shift correlation sequence as optimized for
polarization transfer via long‐range 13C 1H coupling constants are described and …