Copper is an essential nutrient whose redox properties make it both beneficial and toxic to
the cell. Recent progress in studying transition metal signalling has forged new links …

Simple Summary Melanoma is a major public health issue that claims the lives of thousands
of people every year. Furthermore, the outlook for the coming years is not encouraging with …

Two new 'hybrid'metallodrugs of Au (III)(AuTAML) and Cu (II)(CuTAML) were designed
featuring a tamoxifen-derived pharmacophore to ideally synergize the anticancer activity of …

Melanoma is a highly aggressive form of skin cancer with a very poor prognosis and
excessive resistance to current conventional treatments. Recently, the application of the …

Platinum-based anticancer drugs currently available in the market are associated with
severe side effects. Therefore, extensive research has been performed to design and …

Metal complexes are of increasing interest as pharmaceutical agents in cancer diagnostics
and therapeutics, while some of them suffer from issues such as limited water solubility and …

Polypyridyl coordinating ligands are common in metal complexes used in medicinal
inorganic chemistry. These ligands possess intrinsic cytotoxicity, but detailed data on this …

Nanomedicine, a promising area of medicine, employs nanosized tools for the diagnosis,
prevention, and treatment of disease. Particularly, liposomes, lipid-based nanovesicles, are …

Melanoma is recognized as the most dangerous type of skin cancer, with high mortality and
resistance to currently used treatments. To overcome the limitations of the available …

Melanoma is the most aggressive type of skin cancer, the incidence and mortality of which
are increasing worldwide. Its extensive degree of heterogeneity has limited its response to …