The main advantages of proton therapy are the reduced total energy deposited in the patient
as compared to photon techniques and the finite range of the proton beam. The latter adds …

Charged particle therapy has been largely driven and influenced by nuclear physics. The
increase in energy deposition density along the ion path in the body allows reducing the …

Purpose: While Monte Carlo particle transport has proven useful in many areas (treatment
head design, dose calculation, shielding design, and imaging studies) and has been …

Abstract GATE (Geant4 Application for Emission Tomography) is a Monte Carlo simulation
platform developed by the OpenGATE collaboration since 2001 and first publicly released in …

Hadron therapy allows for highly conformal dose distributions and better sparing of organs-
at-risk, thanks to the characteristic dose deposition as function of depth. However, the quality …

PURPOSE: To calculate the linear energy transfer (LET) distributions in patients undergoing
proton therapy. These distributions can be used to identify areas of elevated or diminished …

This paper assesses the contribution of secondary particles to pencil and passively
scattered proton beams, in particular when considering the dose-averaged linear energy …

Purpose To investigate the feasibility and potential clinical benefit of linear energy transfer
(LET) guided plan optimization in intensity modulated proton therapy (IMPT). Methods and …

The purpose of this study was to assess the possibility of introducing site-specific range
margins to replace current generic margins in proton therapy. Further, the goal was to study …

This study reports the investigation of different GEANT4 settings for proton therapy
applications in the context of Treatment Planning System comparisons. The GEANT4. 9.2 …