Overview of side-effects of antibacterial fluoroquinolones: new drugs versus old drugs, a step forward in the safety profile?

A Rusu, AC Munteanu, EM Arbănași, V Uivarosi - Pharmaceutics, 2023 - mdpi.com
Antibacterial fluoroquinolones (FQs) are frequently used in treating infections. However, the
value of FQs is debatable due to their association with severe adverse effects (AEs). The …

Importance of magnesium status in COVID-19

F Guerrero-Romero, O Micke, LE Simental-Mendía… - Biology, 2023 - mdpi.com
Simple Summary Magnesium is an essential nutrient, also called an essential mineral or
element. Magnesium is vastly important in all life, with vital roles for the healthy functioning …

New efforts toward aminothiazolylquinolones with multitargeting antibacterial potential

J Zhang, N Battini, JM Ou, SL Zhang… - Journal of Agricultural …, 2023 - ACS Publications
New antibacterial 3-(aminothiazolyl) quinolones (ATQs) were designed and efficiently
synthesized to counteract the growing multidrug resistance in animal husbandry. Bioactive …

[HTML][HTML] Ciprofloxacin

T Thai, BH Salisbury, PM Zito - StatPearls [internet], 2023 - ncbi.nlm.nih.gov
Ciprofloxacin - StatPearls - NCBI Bookshelf US flag An official website of the United States
government Here's how you know NIH NLM Logo Access keys NCBI Homepage MyNCBI …

Ciprofloxacin release and corrosion behaviour of a hybrid PEO/PCL coating on Mg3Zn0. 4Ca alloy

L Moreno, C Wang, SV Lamaka… - Journal of Functional …, 2023 - mdpi.com
In the present work, a hybrid hierarchical coating (HHC) system comprising a plasma
electrolytic oxidation (PEO) coating and a homogeneously porous structured …

Titanium modification using bioactive titanate layer with divalent ions and coordinated ciprofloxacin–Assessment of drug distribution using FT-IR imaging

M Sandomierski, M Jakubowski, M Ratajczak… - … Acta Part A: Molecular …, 2024 - Elsevier
The paper presents a new method of titanium alloy (Ti6Al4V) modification using bioactive
titanate layers containing various divalent ions (Ca 2+, Mg 2+, Sr 2+, Zn 2+) and surface …

[HTML][HTML] Preliminary studies of antimicrobial activity of new synthesized hybrids of 2-thiohydantoin and 2-quinolone derivatives activated with blue light

A Kania, W Tejchman, AM Pawlak, K Mokrzyński… - Molecules, 2022 - mdpi.com
Thiohydantoin and quinolone derivatives have attracted researchers' attention because of a
broad spectrum of their medical applications. The aim of our research was to synthesize and …

Hierarchical Hybrid Coatings with Drug-Eluting Capacity for Mg Alloy Biomaterials

A Nicolao-Gómez, E Martínez-Campos, L Moreno… - Materials, 2023 - mdpi.com
A hierarchical hybrid coating (HHC) comprising a ceramic oxide layer and two
biodegradable polymeric (polycaprolactone, PCL) layers has been developed on Mg3Zn0 …

An AI approach to generating MIDD assets across the drug development continuum

JS Barrett, RK Goyal, J Gobburu, S Baran, J Varshney - The AAPS Journal, 2023 - Springer
Abstract Model-informed drug development involves developing and applying exposure-
based, biological, and statistical models derived from preclinical and clinical data sources to …

[HTML][HTML] Antacids

BH Salisbury, JM Terrell - 2018 - europepmc.org
Objectives: Identify the mechanism of action antacids. Summarize the indications for antacid
therapy, including relevant interactions with other medications. Review the potential adverse …