The emerging role of mass spectrometry-based proteomics in drug discovery
Proteins are the main targets of most drugs; however, system-wide methods to monitor
protein activity and function are still underused in drug discovery. Novel biochemical …
protein activity and function are still underused in drug discovery. Novel biochemical …
Artificial intelligence in cancer target identification and drug discovery
Artificial intelligence is an advanced method to identify novel anticancer targets and discover
novel drugs from biology networks because the networks can effectively preserve and …
novel drugs from biology networks because the networks can effectively preserve and …
Therapeutic target database update 2022: facilitating drug discovery with enriched comparative data of targeted agents
Drug discovery relies on the knowledge of not only drugs and targets, but also the
comparative agents and targets. These include poor binders and non-binders for developing …
comparative agents and targets. These include poor binders and non-binders for developing …
Utilizing graph machine learning within drug discovery and development
Graph machine learning (GML) is receiving growing interest within the pharmaceutical and
biotechnology industries for its ability to model biomolecular structures, the functional …
biotechnology industries for its ability to model biomolecular structures, the functional …
Artificial intelligence in drug discovery: applications and techniques
Artificial intelligence (AI) has been transforming the practice of drug discovery in the past
decade. Various AI techniques have been used in many drug discovery applications, such …
decade. Various AI techniques have been used in many drug discovery applications, such …
Improving target assessment in biomedical research: the GOT-IT recommendations
CH Emmerich, LM Gamboa, MCJ Hofmann… - Nature reviews Drug …, 2021 - nature.com
Academic research plays a key role in identifying new drug targets, including understanding
target biology and links between targets and disease states. To lead to new drugs, however …
target biology and links between targets and disease states. To lead to new drugs, however …
[HTML][HTML] Integrative multi-omics approaches in cancer research: from biological networks to clinical subtypes
YJ Heo, C Hwa, GH Lee, JM Park, JY An - Molecules and cells, 2021 - Elsevier
Multi-omics approaches are novel frameworks that integrate multiple omics datasets
generated from the same patients to better understand the molecular and clinical features of …
generated from the same patients to better understand the molecular and clinical features of …
Mass spectrometry‐based high‐throughput proteomics and its role in biomedical studies and systems biology
There are multiple reasons why the next generation of biological and medical studies
require increasing numbers of samples. Biological systems are dynamic, and the effect of a …
require increasing numbers of samples. Biological systems are dynamic, and the effect of a …
Sprouts and microgreens: Trends, opportunities, and horizons for novel research
A Galieni, B Falcinelli, F Stagnari, A Datti, P Benincasa - Agronomy, 2020 - mdpi.com
Sprouts and microgreens have attracted tremendous interest across multiple disciplines in
recent years. Here, we critically review the most recent advances to underscore research …
recent years. Here, we critically review the most recent advances to underscore research …
Unrealized targets in the discovery of antibiotics for gram-negative bacterial infections
U Theuretzbacher, B Blasco, M Duffey… - Nature Reviews Drug …, 2023 - nature.com
Advances in areas that include genomics, systems biology, protein structure determination
and artificial intelligence provide new opportunities for target-based antibacterial drug …
and artificial intelligence provide new opportunities for target-based antibacterial drug …