Multiphoton microscopy has rapidly gained popularity in biomedical imaging and materials
science because of its ability to provide three-dimensional images at high spatial and …

Coherent Raman scattering (CRS) microscopy is a chemical imaging modality that provides
contrast based on intrinsic biomolecular vibrations. To date, endeavors on instrumentation …

Hyperspectral stimulated Raman scattering (SRS) imaging has rapidly become an emerging
tool for high content analyses of cell and tissue systems. The label-free nature of SRS …

Carbon-based black pigments, a widely used class of pigments, are difficult to differentiate
with the noninvasive techniques currently used in cultural heritage science. We use pump …

Abstract Objective and Impact Statement. Molecular signatures are needed for early
diagnosis and improved treatment of metastatic melanoma. By high-resolution multimodal …

Excited state dynamics provides an intrinsic molecular contrast of samples examined. These
dynamics can be monitored by pump probe spectroscopy which measures the change in …

Significance Quantitative oblique back-illumination microscopy (qOBM) is a recently
developed label-free imaging technique that enables 3D quantitative phase imaging of thick …

The layering structure of a painting contains a wealth of information about the artist's choice
of materials and working methods, but currently, no 3D noninvasive method exists to replace …

Ultraviolet (UV) spectroscopy is a powerful tool for quantitative (bio) chemical analysis, but
its application to molecular imaging and microscopy has been limited. Here we introduce …

Infrared (IR) spectroscopic imaging is potentially useful for digital histopathology as it
provides spatially resolved molecular absorption spectra, which can subsequently yield …