In the area of parenteral controlled release formulations, in situ forming implants (ISFI) are
attractive alternatives to preformed implants and microparticles. ISFI avoid the use of large …

In situ forming implants (ISI) based on phase separation by solvent exchange represent an
attractive alternative to conventional preformed implants and microparticles for parenteral …

In situ forming implants, defined as liquid formulations that generate solid or semisolid
depots following administration, have shown a range of advantages in drug delivery. This …

Here we report an ultra-long-acting tunable, biodegradable, and removable polymer-based
delivery system that offers sustained drug delivery for up to one year for HIV treatment or …

Protein and peptide macromolecules have emerged as promising therapeutic agents in
recent years. However, their delivery to the target site can be challenging owing to their …

In situ forming (ISF) drug delivery implants have gained tremendous levels of interest over
the last few decades. This is due to their wide range of biomedical applications such as in …

The excellent properties of polyesters combined with their ease of synthesis and
modification enabled their wide use in the pharmaceutical industry. This has been translated …

Ultra-long-acting delivery platforms for HIV pre-exposure prophylaxis (PrEP) may increase
adherence and maximize public health benefit. We report on an injectable, biodegradable …

In situ forming drug delivery implants offer an attractive alternative to pre-formed implant
devices for local drug delivery due to their ability to deliver fragile drugs, simple …

As a result of the low oral bioavailability of several drugs, there is a renewed interest for
parenteral administration to target their absorption directly into the blood bypassing the long …