Glycolysis–a key player in the inflammatory response
G Soto‐Heredero, MM Gómez de Las Heras… - The FEBS …, 2020 - Wiley Online Library
The inflammatory response involves the activation of several cell types to fight insults
caused by a plethora of agents, and to maintain the tissue homoeostasis. On the one hand …
caused by a plethora of agents, and to maintain the tissue homoeostasis. On the one hand …
Involvement of astrocytes in Alzheimer's disease from a neuroinflammatory and oxidative stress perspective
RE González-Reyes, MO Nava-Mesa… - Frontiers in molecular …, 2017 - frontiersin.org
Alzheimer disease (AD) is a frequent and devastating neurodegenerative disease in
humans, but still no curative treatment has been developed. Although many explicative …
humans, but still no curative treatment has been developed. Although many explicative …
Novel therapeutic approaches for Alzheimer's disease: an updated review
Alzheimer's disease (AD) is a progressive neurodegenerative disease and accounts for
most cases of dementia. The prevalence of AD has increased in the current rapidly aging …
most cases of dementia. The prevalence of AD has increased in the current rapidly aging …
Regulation of ketone body metabolism and the role of PPARα
M Grabacka, M Pierzchalska, M Dean… - International journal of …, 2016 - mdpi.com
Ketogenesis and ketolysis are central metabolic processes activated during the response to
fasting. Ketogenesis is regulated in multiple stages, and a nuclear receptor peroxisome …
fasting. Ketogenesis is regulated in multiple stages, and a nuclear receptor peroxisome …
Neuroinflammation and Parkinson's disease—From neurodegeneration to therapeutic opportunities
B Araújo, R Caridade-Silva, C Soares-Guedes… - Cells, 2022 - mdpi.com
Parkinson's disease (PD) is the second most prevalent neurodegenerative disorder
worldwide. Clinically, it is characterized by a progressive degeneration of dopaminergic …
worldwide. Clinically, it is characterized by a progressive degeneration of dopaminergic …
Glial cells in Alzheimer's disease: From neuropathological changes to therapeutic implications
MS Uddin, LW Lim - Ageing research reviews, 2022 - Elsevier
Alzheimer's disease (AD) is a neurodegenerative disorder that usually develops slowly and
progressively worsens over time. Although there has been increasing research interest in …
progressively worsens over time. Although there has been increasing research interest in …
Milestone Review: Metabolic dynamics of glutamate and GABA mediated neurotransmission—The essential roles of astrocytes
JV Andersen, A Schousboe - Journal of Neurochemistry, 2023 - Wiley Online Library
Since it was first generally accepted that the two amino acids glutamate and GABA act as
principal neurotransmitters, several landmark discoveries relating to this function have been …
principal neurotransmitters, several landmark discoveries relating to this function have been …
Glial cells as therapeutic approaches in brain ischemia-reperfusion injury
IH Hernández, M Villa-González, G Martín, M Soto… - Cells, 2021 - mdpi.com
Ischemic stroke is the second cause of mortality and the first cause of long-term disability
constituting a serious socioeconomic burden worldwide. Approved treatments include …
constituting a serious socioeconomic burden worldwide. Approved treatments include …
Curcumin as prospective anti-aging natural compound: focus on brain
T Benameur, R Soleti, MA Panaro, ME La Torre… - Molecules, 2021 - mdpi.com
The nutrients and their potential benefits are a new field of study in modern medicine for
their positive impact on health. Curcumin, the yellow polyphenolic compound extracted from …
their positive impact on health. Curcumin, the yellow polyphenolic compound extracted from …
Molecular communication of a dying neuron in stroke
When a main artery of the brain occludes, a cellular response involving multiple cell types
follows. Cells directly affected by the lack of glucose and oxygen in the neuronal core die by …
follows. Cells directly affected by the lack of glucose and oxygen in the neuronal core die by …